Publications by authors named "Laura Dewald"
Article Synopsis
- The study focuses on the effects of various bioactive compounds on the inflammation related to senescent (aging) preadipocytes, which are fat cells, and how these compounds may modulate harmful signaling in obesity.
- Various methods were used, including treating cells with bromodeoxyuridine to induce senescence, measuring specific enzyme activity, and analyzing cytokine levels to assess inflammation changes.
- Results indicated that compounds like EGCG and resveratrol demonstrated potential to reduce inflammation markers and affect cell aging, suggesting they could be beneficial in managing obesity-related inflammation.
Naturally occurring RNAs are known to exhibit a high degree of modularity, whereby specific structural modules (or motifs) can be mixed and matched to create new molecular architectures. The modular nature of RNA also affords researchers the ability to characterize individual structural elements in controlled synthetic contexts in order to gain new and critical insights into their particular structural features and overall performance. Here, we characterized the binding affinity of a unique loop-receptor interaction found in the tetrahydrofolate (THF) riboswitch using rationally designed self-assembling tectoRNAs.
View Article and Find Full Text PDFWe measured sap flux in Pinus ponderosa Laws. and Pinus flexilis James trees in a high-elevation meadow in northern Arizona that has been invaded by conifers over the last 150 years. Sap flux and environmental data were collected from July 1 to September 1, 2000, and used to estimate leaf specific transpiration rate (El), canopy conductance (Gc) and whole-plant hydraulic conductance (Kh).
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