Publications by authors named "Laura Dethier"

Article Synopsis
  • - The study addresses the challenges in understanding how specific microbes colonize plant roots due to technical issues in metatranscriptomics, such as the abundance of host or microbe rRNA and lack of reference genomes.
  • - Researchers recolonized germ-free Arabidopsis thaliana with a diverse mix of well-characterized bacterial and fungal isolates, enabling a detailed analysis of gene expression at the soil-root interface.
  • - They identified over 3,000 differentially regulated microbial genes, highlighting key processes like translation and energy production, and confirmed that certain genes are essential for root colonization in one prolific bacterial strain, showcasing both unique and shared pathways among microbes.
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Pattern-triggered immunity (PTI) in plants is mediated by cell surface-localized pattern recognition receptors (PRRs) upon perception of microbe-associated molecular pattern (MAMPs). MAMPs are conserved molecules across microbe species, or even kingdoms, and PRRs can confer broad-spectrum disease resistance. Pep-13/25 are well-characterized MAMPs in species, which are renowned devastating oomycete pathogens of potato and other plants, and for which genetic resistance is highly wanted.

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