Publications by authors named "Laura De Paoli"
From the day we are born, the nervous system is subject to insult, disease and degeneration. Aberrant phosphorylation states in neurofilaments, the major intermediate filaments of the neuronal cytoskeleton, accompany and mediate many pathological processes in degenerative disease. Neuronal damage, degeneration and death can release these internal components to the extracellular space and eventually the cerebrospinal fluid and blood.
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- - This paper introduces an action framework designed for countries with low tuberculosis (TB) incidence aiming to eliminate the disease, emphasizing a step-by-step approach towards "pre-elimination" and eventual complete elimination of TB.
- - The framework identifies challenges faced by low-incidence countries, such as decreased political commitment, funding, and awareness as TB rates decline, along with issues related to vulnerable populations and cross-border migration.
- - Eight priority action areas are outlined to tackle these challenges, including ensuring political support, addressing the needs of at-risk groups, and investing in research, all while emphasizing a multisectoral approach to ensure equitable access to TB diagnosis and treatment.