Introduction: Research shows that ICT is beneficial for academics and students, aiding in overcoming distance barriers, streamlining administration, and improving teaching and learning processes. However, the negative impact of technology, particularly technostress, are garnering attention. In the context of the concerns about technostress among higher education institutions (HEI), the aim of the study is to analyze the technostress creators and inhibitors for university teachers and students in different European countries.
View Article and Find Full Text PDFGrain legumes are fair sources of protein, amino acids and energy, and can be used as a replacement for soybean meal in poultry feed formulations as the soybean meal becomes short in supply and costly. However, a concern associated with the use of grain legumes in poultry feeding is the presence of antinutritional factors. The effective processing and utilisation of these grain legumes in poultry feeding are well documented.
View Article and Find Full Text PDFBackground: It is unclear whether an implantable cardioverter-defibrillator (ICD) is generally beneficial in survivors of out-of-hospital cardiac arrest (OHCA).
Objective: We studied the association between ICD implantation prior to discharge and survival in patients with cardiac aetiology or initial shockable rhythm in OHCA.
Design: We conducted a retrospective cohort study in the Swedish Registry for Cardiopulmonary Resuscitation.
Unlabelled: - Objective: To explore the clinical validity of elastic deformation of optical coherence tomography (OCT) images for data augmentation in the development of deep-learning model for detection of diabetic macular edema (DME).
Methods: Prospective evaluation of OCT images of DME (n = 320) subject to elastic transformation, with the deformation intensity represented by ([Formula: see text]). Three sets of images, each comprising 100 pairs of scans (100 original & 100 modified), were grouped according to the range of ([Formula: see text]), including low-, medium- and high-degree of augmentation; ([Formula: see text] = 1-6), ([Formula: see text] = 7-12), and ([Formula: see text] = 13-18), respectively.
The COVID-19 pandemic represents an event that placed humanity in a context where confrontation with uncertainty, isolation, life threats, and significant changes in one's life were on a scale that exceeded by far any previous individual or community crises. The interest of the present research was to investigate the relationship between meaning in life (MiL) and existential anxiety (EA) with personal internal resources such as creativity, playfulness, well-being, and personal meaning. A total of 451 participants from 48 countries (mean age 34.
View Article and Find Full Text PDFCalcium (Ca) plays an essential role in poultry nutrition as 99% of Ca is located in birds' skeletal system. However, oversupply of Ca rather than deficiency of Ca is the current concern in commercial broiler diets. Calcium is an inexpensive dietary nutrient due to the cheap and abundant availability of limestone, the major Ca source; therefore, little attention was given to the oversupply of Ca in the past.
View Article and Find Full Text PDFBackground: This study describes a simple technique for the treatment of kissing choroidal detachment. In contrast to the commonly used technique, this technique is minimally invasive, fast, sutureless, and does not require access to the vitreous space.
Methods: A maintainer is inserted into the anterior chamber.
Continuous processing is the future production method for monoclonal antibodies (mAbs). A fully continuous, fully automated downstream process based on disposable equipment was developed and implemented inside the MoBiDiK pilot plant. However, a study evaluating the comparability between batch and continuous processing based on product quality attributes was not conducted before.
View Article and Find Full Text PDFContinuous production of monoclonal antibodies is gaining more and more importance. To ensure continuous flow through the entire process as well as viral safety, continuous viral clearance needs to be investigated as well. This study focuses on low pH viral inactivation inside a coiled flow inverter (CFI).
View Article and Find Full Text PDFThe continuous production of monoclonal antibodies (mAbs) with the help of disposable equipment poses one of the future major changes in the pharmaceutical industry. Consequently, continuous viral clearance needs to be developed as well. The coiled flow inverter (CFI) was successfully implemented in the continuous downstream as a residence time module for low pH viral inactivation.
View Article and Find Full Text PDFIn contrast to temperate Harmful Algal Blooms (HABs), knowledge on the mechanisms driving tropical HABs are less well studied. The interaction of a seasonal temperature window, cysts (for certain species) and large-scale transport are some of the key processes in temperate HABs. In the Philippines, HABs occur not along long open coastlines, but in embayments that are highly influenced by run-off and stratification.
View Article and Find Full Text PDFContinuous processing for the production of monoclonal antibodies (mAb) gains more and more importance. Several solutions exist for all the necessary production steps, leading to the possibility to build fully continuous processes. Low pH viral inactivation is a part of the standard platform process for mAb production.
View Article and Find Full Text PDFGlaucoma is a chronic neurodegenerative optic nerve disease. Treatment is intended to prevent the development and progression of optic nerve damage by lowering intraocular pressure (IOP). Current therapy options include topical/systemic drugs that increase aqueous humor outflow or decrease its production, laser therapy that targets the trabecular meshwork and ciliary body, and incisional surgery.
View Article and Find Full Text PDFWe present a synoptic, participatory vulnerability assessment tool to help identify the likely impacts of climate change and human activity in coastal areas and begin discussions among stakeholders on the coping and adaptation measures necessary to minimize these impacts. Vulnerability assessment tools are most needed in the tropical Indo-Pacific, where burgeoning populations and inequitable economic growth place even greater burdens on natural resources and support ecosystems. The Integrated Coastal Sensitivity, Exposure, and Adaptive Capacity for Climate Change (I-C-SEA Change) tool is built around a series of scoring rubrics to guide non-specialists in assigning scores to the sensitivity and adaptive capacity components of vulnerability, particularly for coral reef, seagrass, and mangrove habitats, along with fisheries and coastal integrity.
View Article and Find Full Text PDFEstablishing the effectiveness of habitat features to act as surrogate measures of diversity and abundance of juvenile reef fish provides information that is critical to coral reef management. When accurately set on a broader spatial context, microhabitat information becomes more meaningful and its management application becomes more explicit. The goal of the study is to identify coral reef areas potentially important to juvenile fishes in Ngederrak Reef, Republic of Palau, across different spatial scales.
View Article and Find Full Text PDFThe development of stents has been a major advancement over balloon angioplasty, improving vessel revascularization in obstructive coronary artery disease. The development of drug-eluting stents (DES) was the next breakthrough, designed to prevent the development of neointimal hyperplasia (restenosis) following percutaneous coronary interventions (PCI). Several DES are currently in various stages of clinical development; these DES use different stent platforms, different antiproliferative drugs and different polymeric coatings that carry the drugs and control their delivery kinetics.
View Article and Find Full Text PDFIn order to establish the allergic etiology of asthma, the clinician must correlate some anamnestic details with those offered by the in vivo and in vitro allergological tests. Some specific allergic anamnestic informations (such as particular conditions of starting or worsening, co-existence of other allergic disorders, family atopic status) can be revealed by any experimented clinician but the performance of cutaneous tests must be done only by an allergology physician. EAACI recommends allergological prick tests as a reference method; it must be done only with standardized extracts; it has the optimal diagnostic sensibility.
View Article and Find Full Text PDFPolymer coatings are essential for local delivery of drug from the stent platform. In designing a DES, it is critical to balance the hydrophilic and hydrophobic components of the polymer system to obtain optimal biocompatibility, while maintaining controlled drug elution. This study investigates the impact of polymer composition of the BioLinx polymer blend on in vitro biocompatibility, as measured by monocytic adhesion.
View Article and Find Full Text PDFBackground: The prevalence of asthma is increasing in developed countries during the past decade. In Romania there are few studies on asthma epidemiology and no data on the trend of the prevalence.
Aims: The authors investigate the prevalence of asthma and associated symptoms in children and evaluate the trend of prevalence 5 years apart.
We introduce an automated benthic counting system in application for rapid reef assessment that utilizes computer vision on subsurface underwater reef video. Video acquisition was executed by lowering a submersible bullet-type camera from a motor boat while moving across the reef area. A GPS and echo sounder were linked to the video recorder to record bathymetry and location points.
View Article and Find Full Text PDFThere has been a vast improvement in access to remotely sensed data in just a few recent years. This revolution of information is the result of heavy investment in new technology by governments and industry, rapid developments in computing power and storage, and easy dissemination of data over the internet. Today, remotely sensed data are available to virtually anyone with a desktop computer.
View Article and Find Full Text PDFTwo isoforms of the human ornithine carrier, ORC1 and ORC2, have been identified by overexpression of the proteins in bacteria and by study of the transport properties of the purified proteins reconstituted into liposomes. Both transport L-isomers of ornithine, lysine, arginine, and citrulline by exchange and by unidirectional mechanisms, and they are inactivated by the same inhibitors. ORC2 has a broader specificity than ORC1, and L- and D-histidine, L-homoarginine, and D-isomers of ornithine, lysine, and ornithine are all substrates.
View Article and Find Full Text PDFThe Purpose: Is the comparative study of surgically solved ocular trauma, within TARGOVISTE and BRASOV county Hospitals.
Material And Method: A retrospective study has been carried out, over a group of 234 patients, analysing comparatively their age, sex, environment background, occurrence circumstances and year season.
Results: The dominance of male patients can be remarked; according to their age, the dominance is between 40 and 55; according to the time period, the greater occurrence is between october and december.