Publications by authors named "Laura Cucurachi"

Article Synopsis
  • - The study aimed to assess the risks and safety of SARS-CoV-2 vaccination for patients with chronic inflammatory neuropathies, particularly looking at relapse rates before and after vaccination.
  • - Involved 336 patients, with 91% vaccinated; 5% experienced mild relapses post-vaccination, while no relapses occurred in unvaccinated patients, indicating a relative risk increase for those who did receive the vaccine.
  • - Overall, the vaccination didn’t strongly correlate with an increased relapse risk, although CIDP patients showed a slightly higher risk compared to the three months before getting vaccinated, with mild side effects being the main safety concerns.
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Objective: Whether migraine modifies after spontaneous cervical artery dissection (sCeAD) more than after other stroke etiologic subtypes has never been adequately investigated.

Methods: In the setting of the Italian Project on Stroke in Young Adults (IPSYS), we compared the course of migraine before and after acute brain infarct in a group of migraine patients with sCeAD and a group of migraine patients whose ischemia was due to a cause other than CeAD (non-CeAD IS), matched by sex, age (± 3 years), and migraine subtype.We applied linear mixed models to evaluate pre-event vs post-event changes and differences between sCeAD and non-CeAD IS patients.

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Importance: Although sparse observational studies have suggested a link between migraine and cervical artery dissection (CEAD), any association between the 2 disorders is still unconfirmed. This lack of a definitive conclusion might have implications in understanding the pathogenesis of both conditions and the complex relationship between migraine and ischemic stroke (IS).

Objective: To investigate whether a history of migraine and its subtypes is associated with the occurrence of CEAD.

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Bilateral facial palsy is a common sign of autoimmune myasthenia gravis (MG). However, facial muscle weakness without clinical signs of extraocular muscle (EOM) involvement is extremely rare. We describe a late onset generalized MG presenting with facial weakness and bulbar signs without EOM deficits.

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Background: The pathogenesis of cognitive deficits in multiple sclerosis (MS) patients is the subject of debate. A causative role of grey matter impairment has been suggested. Acetylcholinesterase inhibitors have been proposed in the treatment of cognitive impairment in MS.

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