Sleep quality is lower in patients with chronic obstructive pulmonary disease (COPD) than in healthy individuals. Hypoventilation during sleep is the most important cause of hypoxemia and the presence of ventilation/perfusion alterations and reduced functional residual capacity probably also plays a significant role. Although episodes of nocturnal saturation can reasonably be supposed to increase morbidity and mortality in these patients, the diagnostic importance of these desaturations has not been demonstrated.
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