Evaluation of the Performance of a 3D-Printed Smartphone-Based Retinal Imaging Device as a Screening Tool for Retinal Pathology in Mozambique.

Low-income countries carry approximately 90% of the global burden of visual impairment, and up to 80% of this could be prevented or cured. However, there are only a few studies on the prevalence of retinal disease in these countries. Easier access to retinal information would allow differential diagnosis and promote strategies to improve eye health, which are currently scarce.

Predictors of selective laser trabeculoplasty success in open angle glaucoma or ocular hypertension: does baseline tonography have a predictive role?

Background: The determinants of success of selective laser trabeculoplasty (SLT) in treatment-naïve patients with open angle glaucoma (OAG) and ocular hypertension (OHT) have not been understood fully. Therefore, we have conducted this study to explore the predictors of success.

Methods: This is a retrospective review of a pre-existing database of patients who had received primary SLT at St Thomas' Hospital, London, UK.

Comparison of Short-term Postoperative Hypotony Rates of 23-gauge 25-gauge Needles in Formation of the Scleral Tract for Baerveldt Tube Insertion into the Anterior Chamber.

Introduction: To compare the early postoperative hypotony rates and intraocular pressure (IOP) in two groups of eyes using either 23-gauge (23G) or 25-gauge (25G) needle in the creation of the anterior chamber entry tract for Baerveldt tube. The primary outcome measure was incidence of hypotony, and secondary outcome measures included comparison of mean IOP and other early complications.

Materials And Methods: Ours was a retrospective case review of consecutive patients who underwent 350 mm Baerveldt implantation in two units over a 2-year period.

Effect of phacoemulsification on facility of outflow.

Purpose: Phacoemulsification has been shown to reduce intraocular pressure (IOP). The mechanism of action is thought to be via increased trabecular outflow facility. However, studies on the relationship between phacoemulsification and outflow facility have been inconsistent.

Aqueous outflow facility after phacoemulsification with or without goniosynechialysis in primary angle closure: a randomised controlled study.

Background: Goniosynechialysis (GSL) to remove peripheral anterior synechiae (PAS) alongside standard cataract surgery has potential theoretical advantages, Published randomised trials, however, have not shown conclusive functional benefits and aqueous outflow changes following GSL are unknown. This study aimed to compare electronic Shiøtz tonographic aqueous outflow facility (TOF) following phacoemulsification with or without GSL in patients with primary angle closure (PAC) and PAC glaucoma. Secondary outcomes were changes in intraocular pressure (IOP) and use of glaucoma medications.

Twenty-four hour intraocular pressure monitoring with the SENSIMED Triggerfish contact lens: effect of body posture during sleep.

Purpose: To determine the difference in relative intraocular pressure (IOP) measured by the SENSIMED Triggerfish (TF) contact lens in flat compared with 30° head-up sleeping positions in patients with progressive primary open-angle glaucoma or normotensive glaucoma, based on recent or recurrent disc haemorrhage.

Design: Prospective, randomised, cross-over, open-label comparative study.

Methods: IOP was monitored for 24 hours using TF on two separate sessions.

Flow Test to Predict Early Hypotony and Hypertensive Phase After Ahmed Glaucoma Valve (AGV) Surgical Implantation.

Purpose: To assess the validity of a preimplantation flow test to predict early hypotony [intraocular pressure (IOP)≤5 mm Hg on 2 consecutive visits and hypertensive phase (HP) (IOP>21 mm Hg) after Ahmed Glaucoma Valve (AGV) implantation.

Patients And Methods: Prospective interventional study on patients receiving an AGV. A preimplantation flow test using a gravity-driven reservoir and an open manometer was performed on all AGVs.

Priming the Ahmed Glaucoma Valve: pressure required and effect of overpriming.

Purpose: To determine the pressure required to prime an Ahmed Glaucoma Valve (AGV) and determine whether the valve can be damaged by "over-priming pressure."

Methods: Three AGVs, a syringe pump, and a manometer were used to assess priming pressure. Balanced salt solution was pumped through the AGV tube at increasing pressures until a jet of fluid was seen to eject from the AGV, as per manufacturer instructions.

Assessment of the quality of glaucoma referral letters based on a survey of glaucoma specialists and a glaucoma guideline.

Objective: To assess the quality of glaucoma referral letters and to report on the results of a survey of glaucoma specialists about referral letter content.

Design: Cross-sectional study.

Participants: A survey of 135 glaucoma specialists and audit of 200 consecutive referral letters to a tertiary glaucoma unit.

Comparison of visual recovery following ex-PRESS versus trabeculectomy: results of a prospective randomized controlled trial.

Purpose: To compare the rate of visual recovery after Ex-PRESS implantation versus standard trabeculectomy.

Patients And Methods: Subjects enrolled in a prospective randomized controlled trial comparing Ex-PRESS to trabeculectomy were analyzed for postoperative changes in visual acuity (VA). Risk factors for visual loss (split fixation, cup-disc ratio, intraocular pressure, visual field mean deviation, and hypotony) were evaluated.

Intraocular pressure monitoring post intravitreal steroids: a systematic review.

The use of intravitreal (IVT) corticosteroids for treatment of posterior segment diseases has increased significantly over the last decade. A commonly recognized complication of IVT steroids is secondary ocular hypertension (OHT) that can occur immediately secondary to direct intraocular volume increase or weeks to months later as a result of increased outflow resistance. We performed a meta-analysis and found 32% (95% confidence interval, 28.

Preimplantation Flow Testing of Ahmed Glaucoma Valve and the Early Postoperative Clinical Outcome.

Purpose: The Ahmed glaucoma valve (AGV) implant is designed to prevent early postoperative hypotony. There is evidence of variation in hypotony rates in clinical trials which may be due to surgical technique variation, entry site leakage or valve defects from 'over priming'. We describe a simple preimplantation gravity driven test to assess valve function after priming that may reduce hypotony rates.

Comparative human aqueous dynamics study between black and white subjects with glaucoma.

Purpose: To compare the baseline aqueous humor dynamics in white Caucasians and patients of African origin with previously untreated primary open-angle glaucoma (POAG) or ocular hypertension (OHT).

Methods: Ninety-one participants were enrolled in this prospective, observational controlled study: 34 black subjects with POAG or OHT, 32 white Caucasian participants with POAG or OHT, and 12 black and 13 white healthy volunteers as the controls. All aqueous humor parameters were taken between 9 AM and 12 noon on the same day.

Effect of primary selective laser trabeculoplasty on tonographic outflow facility: a randomised clinical trial.

Purpose: To investigate the effect of 180° versus 360° primary selective laser trabeculoplasty (SLT) on tonographic outflow facility and intraocular pressure (IOP).

Design: Prospective, single masked randomised clinical trial.

Participants: Patients with untreated primary open angle glaucoma or ocular hypertension both with IOP > 21-35 mmHg.