Publications by authors named "Laura Banciu"
Mohs micrographic surgery (MMS) is a precise skin surgery technique that is particularly useful in the treatment of high-risk skin cancers and tumors located in challenging anatomical areas. we report two cases of basal cell carcinoma located in the acral areas effectively treated using MMS. the presented cases demonstrate that MMS is an excellent surgical modality providing outstanding medical, cosmetic, and functional outcomes.
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- HPV is a double-stranded DNA virus that often causes asymptomatic infections, with about 90% resolving on their own, but high-risk strains can lead to cancerous lesions in areas like the cervix and anus.
- The virus is known to contribute to various malignancies, particularly via its beta strains in skin cancers such as cutaneous squamous cell carcinoma, though its exact role in other skin cancers remains unclear.
- Recent studies suggest that HPV may also play a role in triggering other skin cancers, like basal cell carcinoma and melanoma, prompting a closer examination of its contributions to both benign and malignant skin lesions.
Herein, we report the case of a 69-year-old patient who presented to our dermatology clinic for a skin eruption characterized by grouped hemorrhagic vesicles and erosions covered by hemorrhagic crusts on an erythematous background located on the lower right limb. The lesions were small, clustered, and variable in size (diameters between one and 10 mm) and located at the level of the L4-L5 dermatomes. The rash had started three to five days after the complete COVID-19 vaccination scheme with the BNT162b2 Pfizer BioNTech vaccine and had been accompanied by a flu-like syndrome.
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- - Bowenoid papulosis is a skin condition linked to HPV infections, which can potentially develop into squamous cell carcinoma, making its diagnosis and treatment important.
- - A 34-year-old non-smoker presented with asymptomatic, pigmented lesions on the penis, leading to a diagnosis confirmed by reflectance confocal microscopy and histopathological exam.
- - Treatment involved Imiquimod and Isoprinosine, resulting in positive progress after 6 weeks, showcasing reflectance confocal microscopy as an effective, non-invasive way to diagnose and monitor treatment response.
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, originating from keratinocytes of the spinous layer. Numerous risk factors have been discovered for the initiation and growth of this type of cancer, such as exposure to UV and ionizing radiation, chemical carcinogens, the presence of immunosuppression states, chronic inflammation, infections with high-risk viral strains, and, last but not least, the presence of diseases associated with genetic alterations. The important socio-economic impact, as well as the difficulty associated with therapy for advanced forms, has made the molecular mechanisms underlying this neoplasia more and more intensively studied, with the intention of achieving a better understanding and advancing the treatment of this pathology.
View Article and Find Full Text PDFBackground: Melanoma is a malignant tumor that determines approximately 80% of deaths as skin cancer-related. The sentinel lymph node (SLN) represents the first filter of tumor cells toward systemic dissemination. The primary objective was to outline the surgical specifics of the sentinel lymph node biopsy (SLNB) technique, correlate the location of the lymph node with the radiotracer load, and identify the characteristics of older patients.
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