Spectral analysis highlight developmental EEG changes in preterm infants without overt brain damage.

Early markers of neurological outcome in the absence of overt brain damage are scarce in extreme prematurity. The aim of this study was to compare spectral EEG values of infants born near term with those of infants born at extremely low gestational age (ELGA) but having attained near term age. We aimed also to evaluate whether spectral EEG features were related with neurological outcome.

Chiari 2 without spinal dysraphism: does it blow a hole in the pathogenesis?

Chiari malformation type 2 is characterized by hindbrain protrusion and a constellation of supratentorial malformations. Chiari malformation type 2 is thought to be causally related to myelomeningocele due to intrauterine cerebrospinal fluid overdrainage. This relationship is so strong that it has become a rule.

Brain magnetic resonance findings in symptomatic congenital cytomegalovirus infection.

Background: Congenital cytomegalovirus (CMV) infection can lead to severe neurological sequelae, but a defined brain magnetic resonance (MR) pattern and MR predictors of clinical outcome are still lacking.

Materials And Methods: Clinical and MR findings of 14 children with symptomatic congenital CMV infection were retrospectively reviewed.

Results: Microcephaly, cerebral palsy and epilepsy were found in eight, six and seven patients, respectively (all concomitant in 6); 12 children developed sensory-neural hearing loss (SNHL).