Publications by authors named "Laura B Dowsett"
Clin Sci (Lond)
October 2024
Article Synopsis
- Symmetric dimethylarginine (SDMA) is a by-product of cellular metabolism linked to endothelial dysfunction and vascular risk, challenging its previously considered inert status.
- The review focuses on SDMA's role in cerebrovascular diseases, particularly ischaemic stroke, examining its impact on factors like nitric oxide signaling, inflammation, and oxidative stress.
- Recent studies indicate a correlation between elevated SDMA levels and poor outcomes in stroke patients, emphasizing the need for further research to understand SDMA's potential as both a marker and mediator of cerebrovascular disease.
