Publications by authors named "Laura Aaron Miller"
Arch Biochem Biophys
April 2003
Article Synopsis
- - The C-terminal alpha-amide group in peptide hormones is formed through a reaction involving a precursor and the enzyme peptidylglycine alpha-amidating monooxygenase (PAM), which cleaves a glycine extension.
- - Glutathione and its S-alkylated forms can act as substrates for PAM, leading to the production of amidated peptides while consuming oxygen and producing glyoxylate in a two-step reaction.
- - Amidated glutathione is not a very effective substrate for glutathione S-transferase, but S-alkylated glutathiones with specific amino acids at the penultimate position, like S-decylglutathione, show improved reactivity in the
