Publications by authors named "Laura A Grimes"
Background: A rapid change in length of cardiac muscle during isometric contraction is followed by developed force that is less than appropriate for the new length because of deactivation of the contractile system. Length change deactivation may have favorable or unfavorable effects on cardiac function, depending on the circumstances under which it is produced.
Methods: Left ventricular papillary muscles from male Sprague-Dawley rats were arranged for recording of isometric force.