Eddy Current Sensor System for Tilting Independent In-Process Measurement of Magnetic Anisotropy.

Modern production equipment is based on the results of quality control as well as process parameters. The magnetic anisotropy of materials is closely connected to internal mechanical stress by the Villari effect, and also to hardening effects due to plastic deformations, and could therefore provide an interesting basis for process control. Nevertheless, the analysis of anisotropic properties is extremely sensitive to sensor and workpiece misalignments, such as tilting.

Molecules in silico: a graph description of chemical reactions.

A general mathematical description, mostly in terms of graph theory, is given for reactions of organic chemistry. The corresponding computer program generates all products that can result from a given set of starting materials interacting according to a given set of reaction schemes. Example reactions from combinatorial chemistry, synthetic organic chemistry, and mass spectroscopic structure elucidation are considered in detail.

MOLGEN-CID--A canonizer for molecules and graphs accessible through the Internet.

The MOLGEN Chemical Identifier MOLGEN-CID is a software module freely accessible via the Internet. For a molecule or graph entered in molfile format (2D) it produces, by a canonical renumbering procedure, a canonical molfile and a unique character string that is easily compared by computer to a similar string. The mode of operation of MOLGEN-CID is detailed and visualized with examples.

Comparison of in-house and commercially prepared haemophilus test media for disk diffusion testing of ampicillin against Haemophilus species.

The performance characteristics of two lots of Haemophilus Test Medium (HTM) prepared in-house at Mayo Clinic, one lot obtained from BBL (Cockeysville, Md.) and one lot obtained from Remel (Lenexa, Kans.), for disk diffusion susceptibility testing of ampicillin against 81 Haemophilus strains were assessed.

Intestinal absorption of D-xylose in the early post-operative period.

To assess intestinal absorption in the early post-operative period, portal and subclavian vein catheters were implanted into 8 pigs. For direct d-xylose infusion into the upper small intestine a feeding tube was inserted via a gastrostomy. Four control animals (Group 1) underwent an open and close laparotomy after catheter and tube implantation.

[Use of the stable nitrogen isotope 15N in assessing liver metabolism in hormonal contraception].

In 37 women with long-term use of oral contraceptives (average use 13.4 years) and 12 women who had not taken oral contraceptives for at least 5 years we determined the serum enzymes ALAT, ASAT, Gamma-GT and conducted the 15N-ammonium test as a marker of partial metabolic performance of the liver. In addition we studied total protein, protein fractions in the serum and haematologic parameter.

[Aspects of healthy and pathologically changed laryngeal epithelium in a model. 2].

Atrophy of laryngeal epithel at aged men can in model according to the literature lead back on prolongation of mitosis cycles. An increasing tendency of cornification and decreasing formation of pegs in range of basilar membrane are also demonstrable. Formation and development of a tumor instance a pathological evolution of tissue in model.

[Resorbate kinetics in the pre- and posthepatic blood compartment in the immediate postoperative phase in swine].

Catheters were implanted in the portal vein by the superior mesenteric vein in pigs for valuation of the absorbant kinetics of enterically applied substances in the mesenteric veins. The blood level kinetics after applying 10 g D-xylose into the jejunum was measured continuously simultaneously in the pre- and posthepatic blood compartment 6, 24, 36, 48, and 72 hours after the operative procedure. An enteric resorption of the pentose is provable already 6 hours after the operation, with their utter normalization in the next 36 hours.

[Healthy and pathologically changed laryngeal epithelium in a model. 1].

This model attempts to consummate the biological processes of laryngeal epithel on a biophysical basis with the end of prediction optimally therapeutic methods.

[Enteral resorption kinetics in the aging process].

With growing age functional and morphological changes in the alimentary tract appear. The age dependence of the intestinal absorption was investigated with the help of the modified D-xylose absorption test. By means of a graphic-mathematical evaluation of the blood level kinetics of D-xylose after oral and intravenous application the absorption rapidity (constant k12), the temporary position of the relative maximum of the D-xylose concentrations in the blood serum after oral application (time tm) and the size of the relative absorption of the small intestine were established depending on the time RR (t).

[Relations between disordered exocrine pancreas function, alcohol consumption and age in alcoholics].

During clinical withdrawal treatment, a disturbed exocrine pancreas function was found in 28 per cent of 72 alcohol addicts, which occurred in connection with an alcohol-induced pancreatitis. The clinical course was mainly quiescent. Altered bicarbonate concentrations and enzyme dissociations were found as a result of the secretin pancreozymin test.

[Involutional peculiarities of digestion and resorption--deduction of preventive and therapeutic needs].

First indication of an age-related alteration of digestive tract can be proseed an age of fourty. In healthy elderly man functional capacity of nutritions is lowered. Normally the digestive capacity will be sufficient provided a reasonable nourishment.

[Alcohol induced damage to the pancreas in patients with increased blood alcohol levels detected in road traffic].

50 patients, driving motor-cars, having increased blood alcohol levels, were registrated and prosecuted. They voluntary underwent catamnestic researches for early diagnosis of alcohol induced lesions of the pancreas. In relation to the habitual drinking systems the study concluded 28 (56 per cent) healthy persons, 13 (26 per cent) alcohol endangered cases, 9 (18 per cent) alcoholics.

A modified D-xylose absorption test.

A modified D-xylose-test is described which enables intestinal absorption to be assessed independently of renal and hepatic function. The speed of appearance of the peak of D-xylose-concentration in plasma after an oral administrated dose and the extent of absorption in the small intestine as a time-function, were analysed by graphic-mathematical evaluation of the kinetics of plasma D-xylose concentration after oral and intravenous administration. Small intestinal functional integrity was assessed in 172 normal individuals (aged from 3 to 96 years), also in 9 patients with coeliac disease.

Age-dependent alterations of intestinal absorption. II. A clinical study using a modified D-xylose absorption test.

With advancing age functional and morphological changes take place within the intestinal tract. The age-dependency of intestinal absorption has been studied using a D-xylose absorption test. The absorption rate (constant k12), the time of appearance of the relative maximum of the D-xylose concentrations in the blood serum after oral administration (time tm), and the extent of the relative absorption in the small intestine as a function of time RA(t) were determined by graphic-mathematical evaluation of the blood level kinetics of D-xylose after oral and intravenous administration.

Age-dependent alterations of intestinal absorption. I. Theoretical aspects.

To test the absorption of orally administered D-xylose in the upper small intestine its concentration in the blood plasma must be measured. Absorption is determined as a function of time by subtraction of the blood values found after intravenous administration, which would indicate the rates of metabolism and extraction of xylose by the body. It is suggested that comparison with the behavior of a proposed four compartment model may give a biological interpretation of the results.

[Function diagnosis of small intestine absorption using the modified D-xylose absorption test].

Based on a biophysical model of the absorptive system a modified D-xylose test has been inaugurated, which is well suited to comprehensively assess the process of intestinal absorption. According to the author's experience of many years the test is a well-suited method for detecting changes in intestinal absorption. It excels by its high validity and reliability.

[Senile changes in the resorption and elimination processes and their importance in pharmacotherapy].

On the basis of experimental and theoretical examinations the senile changes in man's absorbent system and renal excretory function were analysed. It was found that intestinal absorption and summary elimination are delayed with advancing years. Practical consequences with regard to dosage and dosage intervals can be derived for geriatric pharmacotherapy.

[Simulation of the effect of biologically active substances in models].

The results obtained from historadioautographic examinations of the epithelium of the small intestine of rats under the action of procaine served as a basis for examining the proliferative system by using a model. The following results have been obtained through computerized simulation: 1. The maximum life-time of the enterocytes is prolonged at constant villous height, which means that on average the villous is studded with older cells than normally.

The influence of biologically active substances on the regenerative processes of enterocytes in the small intestine of the rat.

The influence of a prolonged treatment with procaine or Turigeran on the cell population kinetics of the mucous membrane of the small intestine was studied by means of 3H-thymidine histoautoradiography in 240 12-month-old male Wistar rats. The investigations produced the following findings: 1. There are no differences in the cell population kinetics of the mucous membrane of the small intestine between procaine- and Turigeran-treated animals.

Age-dependencies in the process of enteric absorption.

Founded upon experimental and theoretical investigation at age-dependence of the absorping system in human beings is analysed. Starting from a compartment model the absorption, velocity of absorption and effectivity of absorption are defined in the physical sense. The experimental investigations results in a general decrease of the velocity of all the processes in the absorping system with increasing age.

[Enteral resorption in the immediate postoperative phase following selective proximal vagotomy].

The postoperative absorption of the small intestine after selective proximal vagotomy was found out by means of the modified D-xylose absorption test in 23 patients on operating day, and on 1st, 5th, 8th, 9th and, 10th postoperative day. The constant of the adsorption speed was reduced on the operating day and decreased further to the 4th postoperative day. Afterwards the preoperative value was obtained approximately.

[Comparative studies of enteral resorption kinetics of D-xylose in humans and experimental pigs].

The enteric transport kinetics of peroral applied D-xylose was comparatively analysed with help of a modified D-xylose absorption test in man and in experimental pig. The animal experimental investigations were carried out in 10 female hybrid pigs at the age of 3 to 8 months. The absorption quickness and the dimension of the effective small intestine absorption in dependence on the time does not show any statistically significant differences between both biological systems.