Effect of photodynamic therapy on the healing of periapical lesions after root canal retreatment: 1-year follow up randomized clinical trial.

Background: The aim of this randomized clinical trial was to evaluate the effects of photodynamic therapy (PDT) after traditional activated final irrigation protocol (ultrasonically activated irrigation, UAI) on periapical lesion healing after single-visit root canal retreatment.

Methods: We included 36 patients with asymptomatic chronic apical periodontitis with periapical lesions larger than 5 mm and teeth sensitive to percussion and palpation, who had previous root canal treatment. All patients who signed informed consent underwent cone-beam computed tomography (CBCT) to determine and calculate the preoperative volume of the periapical lesion.

Applicability of the Demirjian, Willems and Haavikko methods in Croatian children.

Age estimation is an inescapable part of every identification process. During growth and development, it is possible to estimate age based on the developmental stages of teeth. The aim of this study was to evaluate three frequently used methods for dental age estimation on a broad sample of Croatian children.

Facial aging trajectories: A common shape pattern in male and female faces is disrupted after menopause.

Objectives: Despite variation in lifestyle and environment, first signs of human facial aging show between the ages of 20-30 years. It is a cumulative process of changes in the skin, soft tissue, and skeleton of the face. As quantifications of facial aging in living humans are still scarce, we set out to study age-related changes in three-dimensional facial shape using geometric morphometrics.

New model for dental age estimation: Willems method applied on fewer than seven mandibular teeth.

Willems method measures the developmental stages of the seven left permanent mandibular teeth and is frequently used for dental age estimation. The aim of this study was to test its accuracy on a large sample of the Croatian population and to develop new models for estimation based on one to seven mandibular teeth. The developmental stages were evaluated on the digital, standardized orthopantomograms of 1868 Croatian children aged 5 to 16.

Unnecessary prescribing of antibiotics to healthy/asymptomatic school-age carriers of potentially pathogenic bacteria.

Objectives: To re-draw attention to the unnecessary prescribing of antibiotics.

Methods: We monitored nasopharyngeal colonization by 3 potentially pathogenic bacteria, Streptococcus pyogenes, Streptococcus pneumoniae, and Haemophilus influenzae type b in 81 children between the ages of 6 and 7 years who attended the same primary school. The children's health status was also monitored, without using antimicrobial treatment for healthy/asymptomatic carriers.

Dose area product in estimation of effective dose of the patients undergoing dental cone beam computed tomography examinations.

Objective: To investigate the relationship of the effective dose and dose area product (DAP) in dental cone beam computed tomography (CBCT) examinations and to propose conversion factors for estimation of effective doses of the patients using DAP. Dependence of organ doses on DAP was also investigated.

Materials And Methods: Different exposure geometries in Cranex3Dx CBCT device were simulated using Monte Carlo simulation and computational anthropomorphic phantom.

A Rare Case of Recurrent Mucoepidermoid Carcinoma of the Nasal Vestibule.

We report a rare case of a large recurrent mucoepidermoid carcinoma (RMEC) in an 81-year-old female smoker, which has originated in the right nasal vestibule. The recurrent tumour was inadequately treated for 6 years. It was a slow-growing tumour for 3 years and then began to enlarge at a higher pace.

Anatomical variations of the frontal sinus and its relationship with the orbital cavity.

The anatomy of the frontal sinus is highly variable and its variations affect the occurrence/course of pathological processes. We investigated its size and relationship to the orbit, searching for patterns that would allow it to be classified anatomically. Cone beam computed tomography was applied to 91 skulls (age range 21-86 years) to determine sinus height, width, length, and length of contact with the orbit in the coronal and sagittal planes.

Dental Age in Orthodontic Patients with Different Skeletal Patterns.

. To evaluate the difference between chronological and dental age, calculated by Willems and Cameriere methods, in various skeletal patterns according to Steiner's ANB Classification. .

Dental Age and Tooth Development in Orthodontic Patients with Agenesis of Permanent Teeth.

. To compare the development of permanent teeth in a group of children with the congenitally missing permanent teeth (CMPT) and corresponding nonaffected group. .

Dose- and time-dependent effects of clodronate on orthodontic tooth movement.

Orthodontic tooth movement is the result of bone remodeling that occurs in periodontal ligament and alveolar bone tissue as a response to mechanical loading of the tooth. The aim of this study is to investigate the time- and dose-response effects of locally administered clodronate on tooth movement. Sixty Wistar rats were randomly assigned to 4 groups of 15 specimens: E1 - application of 10 mMol of clodronate in 3-day intervals; E2 - application of 2.

Growth hormone positive effects on craniofacial complex in Turner syndrome.

Objective: Turner syndrome occurs in phenotypic females with complete or partial absence of X chromosome. The leading symptom is short stature, while numerous but mild stigmata manifest in the craniofacial region. These patients are commonly treated with growth hormone to improve their final height.

Dental stigmata and enamel thickness in a probable case of congenital syphilis from XVI century Croatia.

Objective: To analyse the dental remains of an individual with signs of congenital syphilis by using macroscopic observation, CBCT and micro-CT images, and the analysis of the enamel thickness.

Design: Anthropological analysis of human skeletal remains from the 16th century archaeological site Park Grič in Zagreb, Croatia discovered a female, 17-20 years old at the time of death, with dental signs supportive of congenital syphilis: mulberry molars and canine defects, as well as non-specific hypoplastic changes on incisors. The focus of the analysis was on three aspects: gross morphology, hypoplastic defects of the molars, canines and incisors, as well as enamel thickness of the upper first and second molars.

Cameriere's third molar maturity index in assessing age of majority.

Estimation of chronological age of an individual is one of the main challenges in forensic science. Legally to be able to treat a person as a minor or an adult, it is necessary to determine whether their age of majority (if they are older or younger than 18, in most countries). Methods for estimating age are especially important when an individual in question lacks personal documents or other means of identification.

Sphenoid sinus types, dimensions and relationship with surrounding structures.

The human sphenoid sinus is an extremely variable cavity and an important landmark in hypophyseal surgery. The aim of this study was to investigate the relationship between the sphenoid sinus type, size, extent of pneumatization and occurrence of protrusions of the adjacent neurovascular structures. A total of 51 randomly selected skulls (≥20 years of age, 33 male; 102 sinuses) were analyzed using cone beam computed tomography to estimate pneumatization extension beyond the body of the sphenoid (planum sphenoidale, pterygoid process, greater wings, clivus, dorsum sellae) and protrusions of the maxillary, mandibular, optic or pterygoid nerve or the internal carotid artery.

Characteristics of the craniofacial complex in Turner syndrome.

Objective: To identify characteristics of the craniofacial complex in Turner syndrome (TS) patients from Croatian population, to investigate the interrelationship among craniofacial variables and to assess their correlation with age.

Design: Cephalometric analysis was carried out on lateral cephalograms of 36 TS patients, aged 10-33 years. Cephalograms of 72 age-matched healthy females with class I occlusion served as control.

The prevalence of lateral incisor hypodontia and canine impaction in Croatian population.

The study investigates the prevalence of second incisor hypodontia and canine impaction in Croatia. The study of incisor hypodontia encompassed 568 examinees (229 boys, 339 girls) aged 6-22 (X = 11.2, SD = 2.

Prevalence of periodontal diseases in Zagreb population, Croatia, 14 years ago and today.

The aim of this study was to assess prevalence of periodontal diseases within Zagreb adult population in 2000. The sample comprised of 412 examinees of both sexes and all age groups. World Health Organization (WHO) methodology and Community Periodontal Index (CPI), (1997) were used.

Dental arch asymmetry in an isolated Adriatic community.

Developmental stability reflects the ability of a genotype to develop in the same way under varying environmental conditions. Deviations from developmental stability, arising from disruptive effects of environmental and genetic stresses, can be measured in terms of fluctuating asymmetry, a particularly sensitive indicator of the ability to cope with these stresses during ontogeny. In an inbred Adriatic island population, we expected dental arch fluctuating asymmetry 1) to be higher than in an outbred sample from the same island, and 2) within this population, to increase with the level of inbreeding.

Holistic anthropological research of Hvar Islanders, Croatia--from parish registries to DNA studies in 33 years.

The complexity of interactions between hereditary, environmental and cultural factors in determining human phenotypes is often underestimated in biomedical research. In this paper, we present 33 years of holistic anthropological research that was being conducted since 1971 in the island of Hvar, Croatia. During this period, detailed characterization of migrations, demography, isonymy, linguistic differences, anthropometric traits (head and body dimensions), physiological (cardio-respiratory) properties, quantitative and qualitative dermatoglyphic traits, radiogrammetric metacarpal bone dimensions and genetic traits (classical antigens, HLA diversity, DNA short tandem repeat -STR, mitochondrial DNA and Y-chromosome polymorphisms) was performed.

Effect of inbreeding and endogamy on occlusal traits in human isolates.

Objective: To discuss the genetic basis of occlusal traits through analysis of the effects of inbreeding in a subdivided isolated community.

Subjects And Methods: The sample comprised dental casts of 224 children, aged 7-14 years, from 15 villages of the Island of Hvar, Croatia.

Main Outcome Measures: Studied traits were Angle class, overjet, vertical bite, overbite, and crowding/spacing.

Longitudinal dental arch changes in the mixed dentition.

The purpose of this study was to investigate dental arch changes that occurred during the mixed dentition in 30 normal occlusion children. Two analyses were done. The first one was at the age of early mixed dentition and the second at the age of late mixed dentition.

Orofacial analysis on the Adriatic islands: an epidemiological study of malocclusions on Hvar Island.

The prevalence of malocclusion was studied on the Hvar island, Croatia. This island is characterized by high rates of endogamy, inbreeding and reproductive isolation. The sample for this study comprised 224 children, 126 males and 98 females from all schools on the island of Hvar (20.

Implant failure: regional versus cumulative evaluation.

In this paper the success rate of implant therapy in various bone regions is discussed. The objective is to determine whether differences existed in success rates of cylinder implants placed in different areas in the both maxilla and mandible. Forty four patients have been treated and reviewed five years after the placement of the fixed prosthetic restoration.

Orofacial analysis on the Adriatic Islands: 1. The island of Hvar as a model for odontogenetic researches.

This paper presents a preliminary orofacial analysis of a subadult population of Hvar, a Croatian island in the Adriatic. Its population represents one of the last genetic isolates in Europe and has therefore been the object of intensive crossdisciplinary research over the last 30 years. We focussed on the coefficient of endogamy on the one hand and malocclusal-related caries on the other hand, and expected differences in the latter between subgroups of the population.