The risk of thromboembolism in relation to in vitro fertilization.

Objective: Summary of available literature concerning recommendation of antithrombotic prophylaxis in the infertility treatment by in vitro fertilization (IVF) and in pregnancies after IVF.

Design: Review article.

Settings: Department of Obstetrics and Gynecology, University Hospital Olomouc, Faculty of Medicine and Dentistry, Palacký University Olomouc; Institute of Medical Genetics, University Hospital Olomouc, Faculty of Medicine and Dentistry, Palacký University Olomouc.

Possibility of Coagulation System Activation Determination with Tissue Factor in Pregnancy Complications.

Background: In this part of the study, where we determined the causes of preeclampsia and other obstetric complications, we focused on the role of tissue factor (TF) in the activation of these pathophysiological processes. Recent findings attribute a significant part of the activation of coagulation creation of autoantibodies. Once this mechanism is activated, the antibodies induce expression of tissue factor (TF, CD142) on monocytes and vascular endothelial cells.

[Recurrent implantation failure and thrombophilia].

Objective: Bring a comprehensive overview of the available knowledge about the importance of thrombophilic mutations in patients with recurrent implantation failure and summary of therapeutic options.

Design: Overview study.

Setting: Department of Obstetric and Gynecology, University Hospital Olomouc.

[HELLP syndrome complicated by liver rupture - case report].

Objective: A case of HELLP syndrome complicated by liver rupture in the 36th week of pregnancy.

Designs: A case report.

Setting: Department of Obstetrics and Gynaecology, FN Olomouc.

Low-level 45,X/46,XX mosaicism is not associated with congenital heart disease and thoracic aorta dilatation:prospective magnetic resonance imaging and ultrasound study.

Objective: To establish the prevalence of risk factors for aortic dissection, such as bicuspid aortic valve, aortic coarctation and ascending aorta dilatation, in women with low-level 45,X/46,XX mosaicism undergoing an in-vitro fertilization (IVF) procedure.

Methods: The study group comprised 25 women with low-level 45,X/46,XX mosaicism (ranging from 3.3% to 10.

[Occurence, etiology and clinical significance of trombocytopenia in pregnancy].

Objective: The principal objective of the study is to compare results from the experimental group of pregnant women suffering from thrombocytopenia in pregnancy with results from the control group of pregnant women with normal physiologic blood platelet count.

Setting: Department of Obstetrics and Gynaecology of the Tomas Bata Regional Hospital Zlín, Obstetrics and Gynaecology Clinic, Haematology and Oncology Clinic of the Palacky University Teaching Hospital and Medical School in Olomouc, Obstetrics and Gynaecology Clinic of the Ostrava Teaching Hospital.

Methodology: A group of 200 pregnant women suffering from thrombocytopenia underwent thorough medical tests.

[Preeclampsia and thrombin generation test].

Objective: Acquiring new information to allow prediction of the development of diseases associated with impaired coagulation. Design effective preventive measures most serious diseases (TEN) in the fields of gynecology and obstetrics. For pregnant women with preeclampsia, hypertension compared with women with normal pregnancies could lead to increased thrombin generation due to the synergistic effect of thrombotic risk factors.

[Compare of misoprostol and dinoprost effectivity by induced second-trimester abortion].

Objectives: To compare the effectivity and safety of second-trimester abortion induced by two different types of prostaglandins.

Type Of Study: Retrospective study.

Setting: Department of Obstetrics and Gynecology, University Hospital Ostrava and Department of Obstetrics and Gynecology, University Hospital Olomouc.

[Thrombin generation test at physiological and risk gravidity].

Unlabelled: Generation of thrombin is pivotal step of hemostasis, according to in vitro experiments, thrombin generation occurs in 2 phases. Initially small amount of thrombin is produced after activation of factor X by complex TF/FVIIa. Thrombin multiplies coagulation by activation of platelets, F V a F VIII.