Synopsis of recent research by authors named "Latifa al-Haj"
Latifa Al-Haj's recent research primarily focuses on the post-transcriptional regulation of gene expression in cancer, revealing how various pathways and elements influence mRNA stability and gene amplification.
Her findings highlight the significant role of the ERBB2/Her2 signaling pathway in promoting mRNA stability through AU-rich elements, elucidating mechanisms of tumor growth and drug resistance.
Additionally, her studies on kinome inhibitors demonstrate the impact of polo-like kinase 1 on post-transcriptional controls, providing insights into potential therapeutic strategies against cancer and chronic inflammatory diseases.