Publications by authors named "Lathrop D"

We conducted avalanching experiments with an external magnetic field and granular samples of different grain sizes (3.18 mm, 6.35 mm, and 8.

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Simultaneous multipass resistive-pulse sensing and fluorescence imaging have been used to correlate the size and fluorescence intensity of individual lipid liposomes composed of polar lipid extracts labeled with membrane-bound 3,3-dioctadecyloxacarbocyanine (DiO) fluorescent molecules. Here, a nanopipet serves as a waveguide to direct excitation light to the resistive-pulse sensing zone at the end of the nanopipet tip. Individual DiO-labeled liposomes (>50 nm radius) were multipassed back and forth through the orifices of glass nanopipets' 110-150 nm radius via potential switching to obtain subnanometer sizing precision, while recording the fluorescence intensity of the membrane-bound DiO molecules.

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Understanding fluid flows in planetary cores and subsurface oceans, as well as their signatures in available observational data (gravity, magnetism, rotation, etc.), is a tremendous interdisciplinary challenge. In particular, it requires understanding the fundamental fluid dynamics involving turbulence and rotation at typical scales well beyond our day-to-day experience.

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We describe the continuous-time dynamics of networks implemented on Field Programable Gate Arrays (FPGAs). The networks can perform Boolean operations when the FPGA is in the clocked (digital) mode; however, we run the programed FPGA in the unclocked (analog) mode. Our motivation is to use these FPGA networks as ultrafast machine-learning processors, using the technique of reservoir computing.

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Fundamental to classical and quantum vortices, superconductors, magnetic flux tubes, liquid crystals, cosmic strings, and DNA is the phenomenon of reconnection of line-like singularities. We visualize reconnection of quantum vortices in superfluid He, using submicrometer frozen air tracers. Compared with previous work, the fluid was almost at rest, leading to fewer, straighter, and slower-moving vortices.

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Over the span of their career, physicians experience changes to their professional role and professional identity. The process of continual adaptation in their work setting incurs losses. These losses can be ambiguous, cumulative, and may require grieving.

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The dynamics of quantized vortices in superfluids has received increased attention recently because of novel techniques developed to visualize them directly. One of these techniques [G. P.

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Cryogenic fluid flows including liquid nitrogen and superfluid helium are a rich environment for novel scientific discovery. Flows can be measured optically and dynamically when faithful tracer particles are dispersed in the liquid. We present a reliable technique for dispersing commercially available fluorescent nanoparticles into cryogenic fluids using ultrasound.

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Quantized vortices are key features of quantum fluids such as superfluid helium and Bose-Einstein condensates. The reconnection of quantized vortices and subsequent emission of Kelvin waves along the vortices are thought to be central to dissipation in such systems. By visualizing the motion of submicron particles dispersed in superfluid (4)He, we have directly observed the emission of Kelvin waves from quantized vortex reconnection.

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Cryogenic flow visualization techniques have been proved in recent years to be a very powerful experimental method to study superfluid turbulence. Micron-sized solid particles and metastable helium molecules are specifically being used to investigate in detail the dynamics of quantum flows. These studies belong to a well-established, interdisciplinary line of inquiry that focuses on the deeper understanding of turbulence, one of the open problem of modern physics, relevant to many research fields, ranging from fluid mechanics to cosmology.

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Spherical Couette flow (flow between concentric rotating spheres) is one of flows under consideration for the laboratory magnetic dynamos. Recent experiments have shown that such flows may excite Coriolis restored inertial modes. The present work aims to better understand the properties of the observed modes and the nature of their excitation.

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High-Reynolds-number flows are common both in nature and industrial applications, but are difficult to attain in laboratory settings using standard test fluids such as air and water. To extend the Reynolds number range, water and air have been replaced at times by low-viscosity fluids such as pressurized air, sulfur hexafluoride, and cryogenic nitrogen gas, as well as liquid and gaseous helium. With a few exceptions, liquid nitrogen has been neglected despite the fact that it has a kinematic viscosity of about a fifth of that of water at room temperature.

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Evolution has provided a number of animal species with extraordinary phenotypes. Several of these phenotypes allow species to survive and thrive in environmental conditions that mimic disease states in humans. The study of evolved mechanisms responsible for these phenotypes may provide insights into the basis of human disease and guide the design of new therapeutic approaches.

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We present measurements of the angular momentum flux (torque) in Taylor-Couette flow of water between independently rotating cylinders for all regions of the (Ω1, Ω2) parameter space at high Reynolds numbers, where Ω1 (Ω2) is the inner (outer) cylinder angular velocity. We find that the Rossby number Ro = (Ω1 - Ω2)/Ω2 fully determines the state and torque G as compared to G(Ro = ∞) ≡ G∞. The ratio G/G∞ is a linear function of Ro(-1) in four sections of the parameter space.

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A new turbulent Taylor-Couette system consisting of two independently rotating cylinders has been constructed. The gap between the cylinders has a height of 0.927 m, an inner radius of 0.

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Spherical Couette flow involves fluid sheared between concentric coaxially rotating spheres. Its scientific relevance lies not only in the simplicity of the system but also in its applicability to astrophysical objects such as atmospheres, oceans, and planetary cores. One common behavior in all rotating flows, including spherical Couette flow, is the presence of inertial modes, which are linear wave modes restored by the Coriolis force.

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We present the use of an alternating current (AC) signal as a means to monitor the conductance of an alpha-hemolysin (alphaHL) pore as a DNA hairpin with a polydeoxyadenosine tail is driven into and released from the pore. Specifically, a 12 base pair DNA hairpin attached to a 50-nucleotide poly-A tail (HP-A(50)) is threaded into an alphaHL channel using a DC driving voltage. Once the HP-A(50) molecule is trapped within the alphaHL channel, the DC driving voltage is turned off and the conductance of the channel is monitored using an AC voltage.

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We observe deterministic chaos in a simple network of electronic logic gates that are not regulated by a clocking signal. The resulting power spectrum is ultrawide band, extending from dc to beyond 2 GHz. The observed behavior is reproduced qualitatively using an autonomously updating Boolean model with signal propagation times that depend on the recent history of the gates and filtering of pulses of short duration, whose presence is confirmed experimentally.

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