Biomed Phys Eng Express
January 2025
Global blindness is substantially influenced by age-related macular degeneration (AMD). It significantly shortens people's lives and severely impairs their visual acuity. AMD is becoming more common, requiring improved diagnostic and prognostic methods.
View Article and Find Full Text PDFThe development of new efficient materials for the removal of water-soluble toxic organic dyes has been one of the focused research areas in the recent past. There is a strong demand for the new materials as most of the reported techniques/materials suffer from serious limitations. In this regard, a series of flexible chitosan-based task-specific polyurethane foams (PUCS-GP, PUCS-CA-GP, PUCS-TA-GP, and PUCS-GA-GP) associated with naturally available hydroxycarboxylic acids was developed.
View Article and Find Full Text PDFMethods Mol Biol
March 2024
Network pharmacology is an emerging pioneering approach in the drug discovery process, which is used to predict the therapeutic mechanism of compounds using various bioinformatic tools and databases. Emerging studies have indicated the use of network pharmacological approaches in various research fields, particularly in the identification of possible mechanisms of herbal compounds/ayurvedic formulations in the management of various diseases. These techniques could also play an important role in the prediction of the possible mechanisms of neuroprotective compounds.
View Article and Find Full Text PDFCyber-Physical Power System (CPPS) refers to a system in which the elements of the internet and the physical power system communicate and work together. With the use of modern communication and information technology, grid monitoring and control have improved. However, the components of a cyber system are extremely vulnerable to cyberattacks via cyber connections due to inadequate cyber security measures.
View Article and Find Full Text PDFSkin is the exposed part of the human body that constantly protected from UV rays, heat, light, dust, and other hazardous radiation. One of the most dangerous illnesses that affect people is skin cancer. A type of skin cancer called melanoma starts in the melanocytes, which regulate the colour in human skin.
View Article and Find Full Text PDFBackground: COVID-19 vaccines have played a crucial role in reducing the burden of the global pandemic. However, recent case reports have indicated the association of the COVID- 19 vaccines with cardiovascular events but the exact association is unclear so far.
Objective: Therefore, the objective of the current study is to find out the association of cardiovascular events with COVID-19 vaccines.
Comb Chem High Throughput Screen
July 2024
Osteoarthritis, which affects an estimated 10% of men and 18% of women over the age of 60 and is increasing in genetic prevalence and incidence, is acknowledged as the condition that degrades the quality of life for older adults in the world. There is currently no known treatment for osteoarthritis. The majority of therapeutic methods slow the progression of arthritis or treat its symptoms, making effective treatment to end the degenerative process of arthritis elusive.
View Article and Find Full Text PDFCleft lip/palate is a common birth defect globally, and the impact of this condition on the dental health of affected individuals can be profound. During intricate rehabilitation of cleft lip and palate patients, the final phase is achieved with definitive prosthodontic treatment. Prosthodontic rehabilitation is often necessary due to missing teeth and the alveolar ridge, malocclusion, residual defects, and the discrepancy between maxillary and mandibular arches.
View Article and Find Full Text PDFBackground: Stress levels increase tremendously in adolescence. Indian adolescents derive much of their stress from school and family pressures. Developing a standardized tool to assess adolescent stress can help early diagnosis.
View Article and Find Full Text PDFAssistive technology for the differently abled and older adults has made remarkable achievements in providing rehabilitative, adaptive, and assistive devices. It provides huge assistance for people with physical impairments to lead a better self-reliant daily life, in terms of mobility, education, rehabilitation, etc. This technology ranges from simple hand-held devices to complex robotic accessories which promote the individual's independence.
View Article and Find Full Text PDFIran J Otorhinolaryngol
November 2022
Introduction: Head and neck is the second most common region for lymphomas. Extranodal lymphomas of the larynx are rare in the pediatric population. Non Hodgkin Lymphoma (NHL) of the larynx is common in the supraglottic region as its rich in lymphoid tissue.
View Article and Find Full Text PDFPlaque deposits in the carotid artery are the major cause of stroke and atherosclerosis. Ultrasound imaging is used as an early indicator of disease progression. Classification of the images to identify plaque presence and intima-media thickness (IMT) by machine learning algorithms requires features extracted from the images.
View Article and Find Full Text PDFThe main objective of the study is to estimate the prevalence and compare the levels of psychological impact, anxiety, depression, and stress experienced by the frontline health care workers (HCWs) during the lockdown and post lockdown periods at Apollo Institute of Medical Sciences and Research, Hyderabad, India. All participants involved in the study were evaluated by using depression, anxiety and stress scale 21, the impact of event scale revised scale for post-traumatic stress disorder (PTSD), and a standardized questionnaire. During the lockdown period, the score for depression was observed mean scores to be more in front desk people (2.
View Article and Find Full Text PDFAtherosclerotic plaque deposit in the carotid artery is used as an early estimate to identify the presence of cardiovascular diseases. Ultrasound images of the carotid artery are used to provide the extent of stenosis by examining the intima-media thickness and plaque diameter. A total of 361 images were classified using machine learning and deep learning approaches to recognize whether the person is symptomatic or asymptomatic.
View Article and Find Full Text PDFBackground: Mortality due to COVID-19 caused by SARS-CoV-2 infection varies among populations. Functional relevance of genetic variations in Angiotensin-converting enzyme 2 () and Transmembrane serine protease 2 (), two crucial host factors for viral entry, might explain some of this variation.
Methods: In this comparative study in Indian subjects, we recruited 510 COVID-19 patients and retrieved DNA from 520 controls from a repository.
Recently the world has come across a pandemic disease known as covid-19. The presence of symptoms of covid-19 and pneumonia may be alike to other types of lung illnesses. So, because of this, it is difficult for the affected person or medical experts to identify the condition.
View Article and Find Full Text PDFLymphedema is a common complication of breast cancer treatment. Yoga is a nonconventional and noninvasive intervention that is reported to show beneficial effects in patients with breast cancer-related lymphedema (BCRL). This study attempted to systematically review the effect of yoga therapy on managing lymphedema, increasing the range of motion (ROM), and quality of life (QOL) among breast cancer survivors.
View Article and Find Full Text PDFBackground: Incontinence-associated dermatitis (IAD) is a potentially serious skin injury that can lead to pressure ulcers (PUs). Many studies have indicated the need for evidence to find the most effective skin care protocol to reduce the incidence and severity of IAD in critically ill patients.
Aim And Objective: To develop a need-based interventional skin care protocol on IAD after identifying the risk of developing IAD in critically ill patients and by assessing the nurse's knowledge and practice on IAD.
Background: A newer trend has been seen recently to reuse the conventional drugs with distinct indications for the newer applications to speed up the drug discovery and development based on earlier records and safety data. Most of the non-cancerous agents could afford a little or tolerable side effects in individuals. However, the repositioning of these non-cancerous agents for successful anticancer therapy is an outstanding strategy for future anti-cancer drug development.
View Article and Find Full Text PDFCardiovasc Hematol Agents Med Chem
December 2021
Natural products have a unique place in the healthcare industry. The genus Commiphora emerged as a potential medicinal source with huge benefits as evidenced through its use in various traditional and modern systems of medicine. Therefore, we aimed to prepare a concise review on the pharmacological activities and the indigenous uses of various plant species belonging to the genus Commiphora along with the structural information of various active botanical ingredients present in these plants based on the published literatures and scientific reports.
View Article and Find Full Text PDFMushrooms have an important role in sustainability since they have long been used as valuable food source and traditional medicine around the world. Regrettably, they are among the most rigorously affected populations, along with several plants and animals, due to the destructive activities of mankind. Thus the authentication and conservation of mushroom species are constantly needed to exploit the remarkable potential in them.
View Article and Find Full Text PDFCurr Med Imaging Rev
June 2020
Background: Carotid artery images indicate any presence of plaque content, which may lead to atherosclerosis and stroke. Early identification of the disease is possible by taking B-mode ultrasound images in the carotid artery. Speckle is the inherent noise content in the ultrasound images, which essentially needs to be minimized.
View Article and Find Full Text PDFStroke is one of the prominent causes of death in the recent days. The existence of susceptible plaque in the carotid artery can be used in ascertaining the possibilities of cardiovascular diseases and long-term disabilities. The imaging modality used for early screening of the disease is B-mode ultrasound image of the person in the artery area.
View Article and Find Full Text PDFEthnopharmacological Relevance: The plants selected for this study, Stereospermum colais and Stereospermum suaveolens are named as Patala in Ayurvedic medicine. Patala is a component of the reputed dasamula (ten roots) used for various imperative Ayurvedic formulations. The roots of Patala have rich traditional value especially in the treatment of inflammation and rheumatism.
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