Analysis of Mycorrhization Trends and Undesired Fungi Species in Three- and Six-Year-Old Plantations in Hungary.

is a key truffle species with significant ecological and economic value. Despite its importance, plantation success can be influenced by soil pH, host plants, and undesired fungi. This study examines how soil pH and host plants influence mycorrhization trends in plantations across six plant species in eight Hungarian settlements, using root sampling and DNA analysis to assess plantations at three and six years of age.

Real-life effectiveness of dupilumab in chronic rhinosinusitis with nasal polyps. Results from eight Hungarian centres with 12-month follow-up.

Background: Research on the immune mechanism behind chronic rhinosinusitis (CRS) has revealed various new endotypes, leading to targeted therapies, especially for severe uncontrolled CRS. Biologics are novel therapeutic strategies providing targeted treatment for the difficult-to-treat recalcitrant CRSwNP patients. Dupilumab is a fully human-derived monoclonal antibody that binds to IL4Rα, inhibiting the signalling of both IL-4 and IL-13.

Achievable agricultural soil carbon sequestration across Europe from country-specific estimates.

The role of soils in the global carbon cycle and in reducing GHG emissions from agriculture has been increasingly acknowledged. The '4 per 1000' (4p1000) initiative has become a prominent action plan for climate change mitigation and achieve food security through an annual increase in soil organic carbon (SOC) stocks by 0.4%, (i.

A "keto-enol" plaque buster mechanism to diminish Alzheimer's β-Amyloid burden.

Curcumin and related compounds have been validated to remove even well-developed human β-amyloid plaques from the brain of transgenic mice, in vivo. However, their molecular mechanism of the plaque buster activity is rather unknown. Computational chemistry was employed here to better understand the β-amyloid protein elimination.

Two Laboratory Deaths, and Keeping Organic Solvents Dry.

The historic evolution of the use of molecular sieves for drying organic solvents, as most likely pioneered by Saul Winstein, is discussed in relation to laboratory safety and the emergence of physical organic chemistry.

Monitoring the clean-up operation of agricultural fields flooded with red mud in Hungary.

In the course of the clean-up operation after the red mud inundation in 2010, red mud was removed from the soil surface in places where the layer was more than 5 cm deep. Before its removal, the red mud seeped into the soil. In 2012, soil samples were taken from depths of 0 to 20 and 20 to 40 cm on some of the affected areas.

The dissolved organic matter as a potential soil quality indicator in arable soils of Hungary.

Although several authors have suggested that the labile fraction of soils could be a potential soil quality indicator, the possibilities and limitations of using the dissolved organic matter (DOM) fraction for this purpose have not yet been investigated. The objective of this study was to evaluate the hypothesis that DOM is an adequate indicator of soil quality. To test this, the soil quality indices (SQI) of 190 arable soils from a Hungarian dataset were estimated, and these values were compared to DOM parameters (DOC and SUVA254).

How an Anglo-American methodology took root in France.

French organic chemistry had a strong nationalistic bent in the immediate aftermath to World War II. It continued to bask in the glow of the pre-World War I Nobel prize awarded jointly in 1912 to Victor Grignard and Paul Sabatier. In addition, the influence of the two mandarins then in power, Charles Prévost at the Sorbonne and Albert Kirrmann, a Dean in Strasbourg who would be called upon as vice-director at the École normale supérieure in Paris, saw to it that the only theory of organic reactions, admissible in the classroom and in the laboratory, was Prévost's.

Quality information from the grapevine.

A letter by Lucien Herr, a highly regarded leading French intellectual at the time of World War I, provides capsule portraits of chemists such as Gabriel Bertrand, Paul Lebeau, Charles Moureu, and Georges Urbain. It makes us better aware of who they were and of how their contemporaries saw their work, which had much to do with their personalities, whether congenial or abrasive. This article is concerned with the kind of information carried by the so-called grapevine.

Examination of Sarmatian age human skeletal remains from the Madaras graves.

The Madaras cemetery is the only one totally excavated Sarmatian site on the Great Hungarian Plain. The cemetery contained 623 graves from the Sarmatian period (from the second century till the middle of the fifth century AD). The preservation of the skeletons are very poor and fragmentary.

Paleopathological and paleodemographical analysis of Sarmatian osteological series originating from southern Hungary.

The Sarmatian are one of the most characteristic people of the Great Hungarian Plain between the 1st and 5th centuries AD. The main purpose of our study was paleodemographical and paleopathological analysis of Sarmatian osteological samples originating from the southern part of the Great Hungarian Plain. During the analysis classical anthropological methods were used.

Increased in vivo platelet activation and reduced intravascular endothelium-derived relaxing factor and nitrate/nitrite production in patients with insulin-dependent diabetes mellitus.

Limited information seems to be available about the role of reduced endothelial production of endotheliumderived relaxing factor (EDRF)-nitrate/nitrite (NO) in the pathogenesis of diabetic angiopathy in insulindependent diabetes. A report of urinary and serum nitrate/nitrite, glucometabolic parameters, endothelial and in vivo platelet activation markers of 22 insulin dependent diabetics (IDDM) patients are given. Urinary and serum nitrate/nitrite concentrations were reduced in IDDM.

[Successful high-dose low-molecular-weight heparin thromboprophylaxis in pregnant women with antiphospholipid syndrome].

Introduction: Antiphospholipid syndrome is an autoimmune disorder, defined as the association of antiphospholipid antibodies with manifestations of venous or arterial thrombosis or pregnancy loss. Primary antiphospholipid syndrome means that the patients have the same clinical symptoms and laboratory findings but they are not suffering from systemic lupus erythematosus or a closely related autoimmune diseases. Secondary antiphospholipid syndrome occurs in association with autoimmune or other diseases.

Use of a platelet filter test in patients with thrombocytosis.

In the differential diagnosis of primary and secondary thrombocytosis platelet function tests may play an important role. We examined the applicability of a platelet filter test (shear-dependent platelet aggregation) as a tool, to differentiate primary thrombocytosis (cases with myeloproliferative disorders) from secondary (reactive) thrombocytosis. The test was carried out in 53 patients suffering from myeloproliferative disorders associated with primary thrombocytosis and in 21 patients with other diseases complicated by secondary thrombocytosis.

Ferrocene: Ironclad History or Rashomon Tale?

What really happened? To recount a pivotal 20th century chemical discovery, the assignment of its structure to ferrocene, ain't easy! One might have thought that telling the story would be straightforward, from published papers and correspondence with some of their authors. Not so. One emerges with a good bit of sympathy for historians of science-who did just what and why is pretty hard to determine, even when less than fifty years have elapsed.

[Thrombophilia, anticoagulant therapy and pregnancy].

Thromboembolic complications during pregnancy are the most common causes of maternal death. Here we report on thromboembolic prophylaxis of 60 pregnancies of 32 pregnant women with familial thrombophilia. Long-term Fraxiparine (Sanofi-Chinoin) as thromboprophylaxis was applied in 26 cases throughout pregnancy.

[The O'Brien filter test in the differential diagnosis of disorders with high-grade thrombocytosis].

In the differential diagnosis of primary and secondary thrombocytosis, platelet function test can be used. We have examined the possible role of O'Brien's filter test in the differentiation of primary and secondary thrombocytosis in 53 patients with myeloproliferative diseases with primary thrombocytosis and in 21 patients with other disorders complicated by secondary thrombocytosis. By using heparin as an anticoagulant, the sensitivity of O'Brien's filter test proved to be 75%, and it's specificity was 85.

The association of reduced endothelium derived relaxing factor-NO production with endothelial damage and increased in vivo platelet activation in patients with diabetes mellitus.

The role of reduced endothelial production of EDRF-NO in the pathogenesis of diabetic angiopathy has received much attention, however, most of the rather conflicting data were gained from animal experiments. Limited human experience seems to be available in insulin dependent diabetes, calling attention to decreased EDRF-NO production. Hereby the clinical, as well as laboratory investigation (urinary and serum nitrate/nitrite, lipid peroxidation, glucometabolic parameters, endothelial and in vivo platelet activation markers, etc.