Publications by authors named "Lasse R Jensen"
Article Synopsis
- * A systematic review, covering studies from 2010 to 2023, evaluated 17 research articles involving 3392 patients, finding that CT scans were the most commonly used imaging method for follow-up after splenic injuries, with 4.5% of patients experiencing vascular issues like pseudoaneurysms.
- * The review reveals a lack of consensus on the optimal timing and methods for radiological follow-up, though routine follow-up is recommended, particularly for higher grade injuries,
Article Synopsis
- The study investigated risk factors for rebleeding and 30-day mortality in patients who underwent prophylactic transarterial embolization for peptic ulcer bleeding at Rigshospitalet, Denmark, from 2016 to 2021.
- Out of 176 patients, 25% experienced rebleeding and 15% died within 30 days; factors like not following a standardized embolization procedure significantly increased these risks.
- More than one endoscopy before the procedure raised rebleeding odds, while a high Rockall-score correlated with increased mortality; factors like active bleeding did not impact these outcomes.
Article Synopsis
- The Kaplan-Meier method can overestimate the risk of cancer coming back, especially when other events like death happen first, but the Aalen-Johansen method can give a more accurate picture by considering these events.
- A study looked at research articles about meningiomas (a type of brain tumor) since 2020 and found that only a few used the better method.
- It showed that not using the Aalen-Johansen method mostly led to overestimating the recurrence risk, especially in older patients with more serious tumors.
Purpose: The Focused Assessment with Sonography for Trauma (FAST) is a tool to rapidly detect intraabdominal and intrapericardial fluid with point-of-care ultrasound. Previous studies have questioned the role of FAST in patients with pelvic fractures. The aim of the present study was to assess the accuracy of FAST to detect clinically significant intraabdominal hemorrhage in patients with pelvic fractures.
View Article and Find Full Text PDFObjectives: To assess the incidence, risk factors, and clinical outcomes of Ogilvie syndrome (OS) in patients with pelvic and/or acetabular fractures.
Design: Retrospective cohort study.
Setting: Level 1 trauma center.
Treatment-refractory meningiomas have a dismal prognosis and limited treatment options. Meningiomas express high-densities of somatostatin receptors (SSTR), thus potentially susceptible to antitumorigenic effects of somatostatin analogues (SSA). Evidence for SSA in meningiomas is scarce, and it is unclear if published literature would either (1) support wider use of SSA, if (2) more evidence is desirable, or if (3) available evidence is sufficient to discard SSA.
View Article and Find Full Text PDFBackground: The standard treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) constitutes of systemic oral corticosteroid. Although oral corticosteroid might revert the acute deafness, some patients with ISSNHL display a more treatment refractory course. For these patients, corticosteroid installed directly into the middle ear has become a more frequent treatment, due to the potential benefits of a high, local concentration compared to a systemic administration.
View Article and Find Full Text PDFTERT promoter mutations have been associated with increased risk of recurrence in meningioma cohorts, thus a potential biomarker for aggressive phenotypes. A main purpose of refining tumour classification is better predictions on the patient level. We compiled data from previous published cohorts to investigate patient-level predictions of recurrence based on TERTp-mut status.
View Article and Find Full Text PDFBackground: We aimed to compare the predictive performance of pN-categories in oral squamous cell carcinoma (OSCC) encompassing the most recent 8th edition (TNM8), its predecessor (TNM7), and a newly proposed algorithm (pN-N), which classifies patients according to the number of positive lymph nodes and extranodal extension.
Methods: Consecutive, primary OSCC patients from seven previously published cohorts were included and classified according to the three pN-classifications: TNM7, TNM8 and pN-N. Overall survival probabilities were summarised with the Kaplan-Meier method.
Somatostatin receptor (SSTR)-targeted peptide receptor radionuclide therapy (PRRT) represents a promising approach for treatment-refractory meningiomas. We performed an individual patient data meta-analysis, including all published data on meningioma patients treated with SSTR-targeted PRRT. The main outcomes were toxicity, response to treatment, progression-free survival (PFS), and overall survival (OS).
View Article and Find Full Text PDFBackground: There are examples of incongruence between the WHO grade and clinical course in meningioma patients. This incongruence between WHO grade and recurrence has led to search for other prognostic histological markers.
Objective: To study the correlation between the Ki-67 proliferative index (PI), risk of recurrence, and recurrence rates in meningioma patients.
The habitability of Mars is determined by the physical and chemical environment. The effect of low water availability, temperature, low atmospheric pressure and strong UV radiation has been extensively studied in relation to the survival of microorganisms. In addition to these stress factors, it was recently found that silicates exposed to simulated saltation in a Mars-like atmosphere can lead to a production of reactive oxygen species.
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