Predicting fetal alcohol spectrum disorders in preschool-aged children from early life factors.

Background: Early life factors, including parental sociodemographic characteristics, pregnancy exposures, and physical and neurodevelopmental features measured in infancy are associated with fetal alcohol spectrum disorders (FASD). The objective of this study was to evaluate the performance of a classifier model for diagnosing FASD in preschool-aged children from pregnancy and infancy-related characteristics.

Methods: We analyzed a prospective pregnancy cohort in Western Ukraine enrolled between 2008 and 2014.

Alcohol-related dysmorphic features as predictors of neurodevelopmental delay in infants and preschool-aged children: Results from a birth cohort in Ukraine.

Background: Cardinal and non-cardinal dysmorphic features are associated with prenatal alcohol exposure (PAE); however, their association with neurodevelopment is less clear. The objective of this study was to determine whether alcohol-related dysmorphic features predict neurodevelopmental delay in infants and toddlers.

Methods: We analyzed a prospective pregnancy cohort in western Ukraine enrolled between 2008 and 2014.

Patterns of Prenatal Alcohol Exposure and Alcohol-Related Dysmorphic Features.

Background: In animal models, it is possible to induce different alcohol-related dysmorphic abnormalities based on the timing of prenatal alcohol exposure (PAE). Our objective was to assess whether patterns of PAE differentially predict alcohol-related dysmorphic features in 415 infants.

Methods: We analyzed a prospective pregnancy cohort in western Ukraine enrolled between 2008 and 2014.