Publications by authors named "Lars Wiuff Andersen"
Background: Hyperkalaemia is a life-threatening electrolyte disturbance and also a potential cause of cardiac arrest. The objective was to assess the effects of acute pharmacological interventions for the treatment of hyperkalaemia in patients with and without cardiac arrest.
Methods: The review was reported according to PRISMA guidelines and registered on PROSPERO (CRD42023440553).
In-hospital cardiac arrest registries and aetiology of cardiac arrest.
Acta Anaesthesiol Scand
November 2024
Background: Piperacillin/tazobactam may be associated with less favourable outcomes than carbapenems in patients with severe bacterial infections, but the certainty of evidence is low.
Methods: The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an investigator-initiated, international, parallel-group, randomised, open-label, adaptive clinical trial with an integrated feasibility phase. We will randomise adult, critically ill patients with sepsis to empirical treatment with meropenem or piperacillin/tazobactam for up to 30 days.
Background: General anesthesia is common, but concerns regarding post-operative complications and mortality remain. No study has described the Danish patient population undergoing general anesthesia on a national level. The aim of this study was to describe the characteristics and outcomes of patients undergoing general anesthesia in Denmark.
View Article and Find Full Text PDFBackground: Intravenous fluids are often used in the treatment of sepsis. The better strategy regarding fluid volume is debated, but preliminary data in patients with septic shock or sepsis-related hypotension favor restrictive fluid administration. We describe the protocol and statistical analysis plan for the Restrictive Fluid Administration vs.
View Article and Find Full Text PDFArticle Synopsis
- Alcohol-use disorders (AUDs) in patients presenting with septic shock are linked to higher mortality rates, and the study focused on thiamine administration patterns in this group.
- Conducted at a tertiary care center from 2008 to 2014, the study analyzed 53 patients with AUDs, noting that 64% received thiamine, often with delays.
- The findings revealed that patients receiving thiamine had a significantly lower mortality rate (44%) compared to those who did not receive it (79%), indicating thiamine's potential protective effect.
Objective: In patients with long-standing diabetes mellitus (DM), there is increasing evidence for abnormal processing of gastrointestinal sensations in the central nervous system. Using magnetic resonance diffusion tensor imaging, we characterized brain microstructure in areas involved in visceral sensory processing and correlated these findings to clinical parameters.
Research Design And Methods: Twenty-six patients with DM and gastrointestinal symptoms and 23 healthy control subjects were studied in a 3T scanner.