Association between left ventricular diastolic function and right ventricular function and morphology in asymptomatic aortic stenosis.

Background: Aortic stenosis (AS) is a progressive disease in which left ventricular (LV) diastolic dysfunction is common. However, the association between diastolic dysfunction and right ventricular (RV) loading conditions and function has not been investigated in asymptomatic AS patients.

Methods And Findings: A total of 41 patients underwent right heart catheterization and simultaneous echocardiography at rest and during maximal supine exercise, stratified according to resting diastolic function.

Relation of Left Atrial Size, Cardiac Morphology, and Clinical Outcome in Asymptomatic Aortic Stenosis.

Left atrial (LA) dilation in asymptomatic severe aortic stenosis (AS) may be an indicator of advanced disease. We aimed to investigate the association between LA volume index and left ventricular (LV) morphology assessed with cardiac magnetic resonance imaging (cMRI), and to assess the association with cardiac events. Ninety-two asymptomatic patients with aortic valve area <1 cm, aortic peak jet velocity >3.

[Stem cell therapy in ischemic heart disease].

Stem cell therapy is a treatment of great potential, including in cardiology. In the past few years, it has been shown that the heart has the potential for regeneration. Clinical studies have shown that intracoronary or intracardiac transplantation of bone marrow stem cells to patients with chronic or acute ischemic heart diseases improves the function and regional myocardial perfusion of the left ventricle.