Publications by authors named "Lars Jansen Sverkeli"
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Synopsis of recent research by authors named "Lars Jansen Sverkeli"
- Lars Jansen Sverkeli's research primarily focuses on the role of nicotinamide adenine dinucleotide (NAD) metabolism in cellular processes and its implications for both toxicology and mitochondrial function in cardiac health.
- His 2021 study on vacor analogs highlights how a rat poison, vacor, disrupts NAD metabolism by converting into a toxic analog, VAD, which could potentially be utilized in cancer therapies.
- In another significant study, he investigates the link between NAD depletion and mitochondrial dysfunction in cardiac cells, illustrating how damage to mitochondrial DNA (mtDNA) can lead to impaired heart function through reduced NAD levels.
