Publications by authors named "Lars C Boberg-Ans"

Artificial intelligence (AI) is becoming increasingly influential in ophthalmology, particularly through advancements in machine learning, deep learning, robotics, neural networks, and natural language processing (NLP). Among these, NLP-based chatbots are the most readily accessible and are driven by AI-based large language models (LLMs). These chatbots have facilitated new research avenues and have gained traction in both clinical and surgical applications in ophthalmology.

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A variety of daily activities can intentionally or unintentionally cause the Valsalva manoeuvre, which induces a physiological response of elevated peripheral venous pressure. Studies have speculated that it may ultimately affect the choroidal anatomy. This is particularly important from a clinical point-of-view since patients occasionally hold their breath while undergoing macular optical coherence tomography (OCT).

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Purpose: To study characteristics and associations of Gunn dots in a cohort of healthy children aged 11 to 12 years.

Methods: As part of the Copenhagen Child Cohort 2000 Study, red-free fundus photographs were taken on 761 healthy children aged 11 to 12 years. The photographs were centered on the optic disk.

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Article Synopsis
  • - Central serous chorioretinopathy (CSC) is a common eye condition linked to various risk factors, including tobacco use, which can be targeted for prevention efforts.
  • - A comprehensive review of studies (covering nearly 28,000 CSC patients) revealed a strong association between tobacco consumption and an increased risk of developing CSC, with an odds ratio of 2.99.
  • - Although the precise reasons for the tobacco-CSC link are not fully understood, quitting smoking is a practical suggestion that can help patients manage their condition, highlighting the need for more research on the benefits of quitting.
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Purpose: To investigate whether phacoemulsification (PE) experience impacts and transfers to the skill acquisition of novices in manual small-incision cataract surgery (MSICS) within a simulation environment.

Setting: Copenhagen Academy for Medical Education and Simulation, Copenhagen, Denmark.

Design: Prospective controlled experimental study.

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Purpose: To compare Manual Small Incision Cataract Surgery (MSICS) microsurgical performance in course participants who received virtual reality simulation-based training by either a surgical expert or a non-ophthalmologist instructor.

Setting: Copenhagen Academy for Medical Education and Simulation, Copenhagen, Denmark.

Design: Randomized controlled trial.

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Central serous chorioretinopathy (CSC) is a prevalent exudative maculopathy and the ongoing verteporfin shortage restricts current treatment possibilities. Topical non-steroidal anti-inflammatory drugs (NSAID) have previously been proposed as a treatment for CSC, although its exact efficacy remains unclear. In this systematic review and meta-analysis, we outlined the efficacy of topical NSAIDs for the treatment of CSC.

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Background: Systematic literature searches are the cornerstone of systematic reviews. In this study, we evaluated database coverage of randomized clinical trials for central serous chorioretinopathy (CSC).

Methods: We searched 12 databases (BIOSIS Previews, CINAHL, the Cochrane Central, Current Contents Connect, Data Citation Index, Derwent Innovations Index, EMBASE, KCI-Korean Journal Database, MEDLINE, PubMed, SciELO Citation Index, and Web of Science Core Collection) on 10 April 2023 for randomized clinical trials for CSC.

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Purpose: To investigate the epidemiology of Gunn's dots and their associations in a population-based cohort of children.

Methods: Red-free fundus photographs from 2,286 children aged 11 years to 14 years from the Sydney Myopia Study were graded. Gunn's dots were manually marked and counted within a 6 mm grid centered on the optic disc.

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