Publications by authors named "Larry P Cahalin"
Effects of Home-Based Electrical Stimulation on Plasma Cytokines Profile, Redox Biomarkers, and Metalloproteinases in the Heart Failure with Reduced Ejection Fraction: A Randomized Trial.
Marianne Lucena da Silva Ivo Vieira de Sousa Neto Alexandra C G B de Lima Fabrício Barin Otávio de Toledo Nóbrega Larry P Cahalin
J Cardiovasc Dev Dis
December 2022
Article Synopsis
- Low-frequency electrical stimulation (LFES) is explored as an alternative for heart failure (HF) patients struggling to exercise, focusing on its effects over 10 weeks on various biomarkers and exercise performance.
- In a study with 24 HF patients, LFES increased active-MMP2 levels while decreasing active-MMP9 levels, indicating some biochemical changes, but did not affect cytokines, redox biomarkers, or overall exercise performance significantly.
- The findings suggest that LFES may help modulate MMP activity, which could support muscle adaptation for future physical demands, although the overall functional benefits appear limited.