Blepharoclonus refers to myoclonic rhythmic eyelid closure. This is an extremely rare abnormal movement of the eyelids. The symptom has an ill-defned anatomical localization and hypothesized etiologies are diverse.
View Article and Find Full Text PDFSubendocardial hemorrhage (SEH) is a striking feature seen in many forensic autopsy cases. It was believed earlier to represent an agonal phenomenon without any particular reference to the cause of death. However, the latest study showed that even minor SEH might have an influence on cardiac function and might be involved in the mechanism of death.
View Article and Find Full Text PDFIntroduction: The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, named statins, are well-established cholesterol-lowering drugs able to reduce cardiovascular risk in hypercholesterolemic patients. The possible effect of statin on bone tissue, so-called pleiotropic effects has received particular attention. Studies reported a positive effect of statin on bone tissue in both of animal and human study by enhancing the expression of the bone morphogenetic proteins (BMPs), in particular of BMP2, which in turn leads to osteoblast differentiation and bone formation including interfering with osteoclastic activity.
View Article and Find Full Text PDFThrombocytopenia commonly occurs in hospitalized patients, particularly critically ill patients. We present an exemplifying case of severe heparin-induced thrombocytopenia (HIT) in an effort to solidify its high priority in the differential diagnosis of thrombocytopenia. A 75-year-old female underwent cardiac surgery with intraaortic balloon pump (IABP) placement.
View Article and Find Full Text PDFWe report a case of E. coli meningitis presented initially without nuchal rigidity. Despite intensive care treatment, CSF was not sterilized and the patient died at 17 days after his admission.
View Article and Find Full Text PDFObjective: The routine turning of immobilized critically ill patients at a minimum of every 2 hrs has become the accepted standard of care. There has never been an objective assessment of whether this standard is achieved routinely. To determine if immobilized patients in the intensive care unit (ICU) receive the prevailing standard of change in body position every 2 hrs.
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