Publications by authors named "Larissa R Stival"

Article Synopsis
  • The study aims to explore how inflammatory biomarkers relate to corneal epithelial measurements in patients with keratoconus compared to healthy individuals.
  • It involved a comparison of tear cytokine levels and hair cortisol concentrations from 100 patients, divided into 48 with keratoconus and 52 healthy controls, using advanced measurement techniques.
  • Results showed that keratoconus patients had significantly higher levels of certain cytokines and cortisol, with notable correlations found between IL6 levels and specific epithelial thickness metrics.
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Purpose: To evaluate measures of corneal epithelium in eyes that showed documented signs of keratoconus (KC) progression and compare with stable eyes and healthy controls. Also, to determine the correlation of these epithelial parameters with maximum keratometry (K max) and pachymetry.

Design: Prospective, observational, comparative study.

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Purpose: To develop a new ectasia risk model through artificial intelligence (AI) and machine learning, enabling the creation of an integrated method without a cut-off point per risk factor, and subsequently better at differentiating patients at higher risk of ectasia with normal topography.

Methods: This comparative case-control study included 339 eyes with normal preoperative topography, with 65 eyes that developed ectasia after laser in situ keratomileusis (ectasia group) and 274 eyes that did not develop ectasia (control group). The AI model used known risk factors to engineer 14 additional ones, totaling 20 features.

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Purpose: To evaluate interleukin (IL) and hair cortisol concentrations (HCCs) in progressive keratoconus (KC) and compare them with KC-stable eyes and healthy control, and to determine the correlation of these inflammatory mediators and HCCs and their relationship with structural damage represented by increased corneal curvature.

Setting: University of Sao Paulo, Brazil.

Design: Prospective observational comparative study.

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Purpose: To provide an overview of the efficacy and safety of available presbyopic excimer laser ablation profiles.

Methods: Literature review.

Results: Monovision with excimer laser traditionally applies near correction to the non-dominant eye.

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Purpose: To evaluate the clinical outcomes of intrastromal corneal ring segment (ICRS) implantation to correct ectasia in eyes with prior refractive surgery.

Methods: Forty-one eyes of 25 patients (13 men, 12 women; mean age, 28.66 years) with ectasia after refractive surgery [photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK)] were included in a nonrandomized, retrospective, observational case series.

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Purpose: To evaluate changes in corneal sensitivity following corneal cross-linking (CXL) in patients with progressive earlier stage keratoconus.

Methods: Thirty-eight eyes of 19 patients (11 women, 8 men) were included in a prospective, nonrandomized clinical study. The mean patient age was 22 years (range, 18-26 years).

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Purpose: To evaluate the clinical outcome(s) and complication(s) of subconjunctival bevacizumab treatment in patients with recurrent pterygium.

Methods: This prospective case series included patients who had undergone pterygium surgery and were diagnosed with recurrent pterygium. All patients received one subconjunctival injection of 0.

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