Publications by authors named "Larissa R Rosa"
Article Synopsis
- * Cornea xenotransplantation using porcine corneas is a potential solution due to the cost-effectiveness and biological compatibility, but there are ethical issues and immune rejection concerns that need to be addressed.
- * Recent advancements in genetic engineering and new immunosuppressive techniques are showing promise in increasing the success rate of porcine corneal transplants, highlighting the need for ongoing research to improve safety and effectiveness.
Ex vivo cultivation and transplantation of limbal epithelial cells has been reported as an alternative source for ocular surface reconstruction. However, until now, the functional improvement of these patients is limited due to the low survival rate of the transplanted cells. Consequently, the clinical benefits of this therapeutic strategy are only temporary and can assign them to paracrine effects associated with the transplanted cells.
View Article and Find Full Text PDF