Three-Dimensional Nanoscale Morphological Surface Analysis of Polymeric Particles Containing Essential Oil.

Biodegradable particles were developed using poly-ε-caprolactone and gelatin carriers containing different concentrations of essential oil (EO) (360 µg/mL, 420 µg/mL, and 460 µg/mL). Atomic force microscopy was useful to evaluate the particles' surface based on morphological parameters. The particles' size varied from 150 nm to 300 nm.