Publications by authors named "Larissa M de Oliveira"
Biodegradable particles were developed using poly-ε-caprolactone and gelatin carriers containing different concentrations of essential oil (EO) (360 µg/mL, 420 µg/mL, and 460 µg/mL). Atomic force microscopy was useful to evaluate the particles' surface based on morphological parameters. The particles' size varied from 150 nm to 300 nm.
View Article and Find Full Text PDFBackground: The prevalence of infection with multidrug-resistant gram-negative bacteria (MDR-GNB) after solid-organ transplantation is increasing. Surveillance culture (SC) seems to be an important tool for MDR-GNB control. The goal of this study was to analyze the performance of SC for MDR-GNB among liver transplant (LT) recipients.
View Article and Find Full Text PDFBackground: Carbapenem-resistant Enterobacteriaceae (CRE) is an emergent microorganism of infections after liver transplant (LT). The aim of this study was to analyze the risk factors for CRE acquisition and infection after LT.
Methods: This was a prospective cohort study involving patients who underwent LT in the 2010 to 2014 period.
Colistin-resistant Enterobacteriaceae infections: clinical and molecular characterization and analysis of in vitro synergy.
Diagn Microbiol Infect Dis
March 2017
Article Synopsis
- * Resistance was linked to chromosome mutations, and treatment varied, with 8 patients on monotherapy and 19 on combination therapy; the overall mortality rate was 37%.
- * In vitro tests showed a 74% synergy rate for combination therapies using colistin, amikacin, and tigecycline, but no significant survival difference was found based on drug combinations; major risk factors for mortality included dialysis and shock.
Background: To describe the clinical and microbiological data of carbapenem-resistant Enterobacteriaceae (CRE) infections, the treatment used, hospital- and infection-related mortality, and risk factors for death.
Methods: A prospective cohort conducted from March 2011 to December 2012. Clinical, demographic, and microbiological data such as in vitro sensitivity, clonality, carbapenemase gene mortality related to infection, and overall mortality were evaluated.
Methicillin-resistant Staphylococcus aureus (MRSA) screening plays a great role in preventing infections in surgical patients. This study aims to evaluate clonality, virulence and resistance of MRSA in pre- and post-liver transplantation (LT) patients. Nasal and groin swabs of 190 patients were collected.
View Article and Find Full Text PDFArticle Synopsis
- S. aureus is a key player in infections among liver transplant patients, yet there's limited research on its virulence factors in this group.
- In a study, MRSA colonization rates were found to be 13% in cirrhotic patients and 23% in post-transplant patients, with SCCmec types I, II, and III prevalent among isolates.
- The study identified new spa and ST types not previously reported in Brazil, highlighting a predominant MRSA cluster linked to the New York/Japanese epidemic clone.