Publications by authors named "Larissa G Rigueto"
Article Synopsis
- Drug-induced hypomagnesemia can have serious and potentially fatal consequences, particularly from long-term use of proton pump inhibitors (PPIs), which impair magnesium absorption in the intestines.
- The mechanisms involve reduced transport of magnesium through specific cellular channels (TRPM6 and TRPM7) and a decrease in paracellular absorption due to downregulated claudins.
- Two cases are highlighted where PPI use led to electrolyte disorders resulting in cardiac arrhythmia, cognitive changes, and seizures, emphasizing the importance of monitoring magnesium levels in high-risk patients.
The "new normal" osmotic threshold: Osmostat reset.
Larissa G Rigueto Henrique M Santiago David J Hadad Antonio Carlos Seguro Adriana Castello C Girardi
Clin Nephrol Case Stud
January 2022
Hyponatremia is the most common electrolyte disorder in hospitalized patients. The syndrome of inappropriate antidiuresis (SIAD) is one of the leading causes of hyponatremia. Although not widely known, SIAD has a vast spectrum of etiologies and differential diagnoses and has been classically divided into four types (A, B, C, D).
View Article and Find Full Text PDF