Publications by authors named "Larissa Duarte"

Consumers have been demanding foods that, besides providing nutrition, bring some health benefits, known as functional foods. The insertion of probiotics in foods is a strategy for developing functional foods. Still, it has been a challenge because these matrices have different pHs and undergo different process temperatures and times that can reduce the viability of these microorganisms.

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Athletes with tetraplegia may experience marked hyperthermia while exercising under environmental heat stress due to their limited ability to dissipate heat through evaporative means. This study investigated the effectiveness of two external cooling strategies (i.e.

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  • The study explores the link between high plasma levels of neurofilament light chain (pNfL) and neurocognitive symptoms in patients with Long COVID, indicating that SARS-CoV-2 can lead to long-term brain effects even after mild illness.
  • A group of 63 Long COVID patients underwent neurocognitive assessments, revealing that those with cognitive issues and fatigue had significantly higher pNfL levels compared to those without these symptoms.
  • The findings suggest that measuring pNfL could help identify individuals at risk for CNS involvement and guide their need for ongoing monitoring and treatment for neurocognitive dysfunction post-COVID.
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  • Chikungunya virus (CHIKV) can lead to severe diseases, including chronic arthritis and, in rare cases, neurological issues and death, primarily transmitted by mosquitoes.
  • A comprehensive study revealed that deaths from CHIKV are linked to multi-organ infections, serious brain damage, and higher levels of inflammation in the body compared to survivors.
  • The research also found that CHIKV infection disrupts the blood-brain barrier, leading to increased permeability and changes in protein expression, enhancing our understanding of CHIK pathophysiology and fatal outcomes.
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SARS-CoV-2 can trigger autoimmune central nervous system (CNS) diseases in genetically susceptible individuals, a mechanism poorly understood. Molecular mimicry (MM) has been identified in other viral diseases as potential triggers of autoimmune CNS events. This study investigated if MM is the process through which SARS-CoV-2 induces the breakdown of immune tolerance.

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Alginate is a biopolymer widely used on delivery systems when bioactive protection at acidic pH is required, while chitosan can enhance mucoadhesion and controlled release at alkaline pHs. In this work, alginate ionotropic gelation and electrostatic complexation to chitosan were evaluated concomitantly or in a two-step approach to improve the delivery properties of systems in different pHs. The effect of pH on alginate gelation and chitosan interactions were also evaluated.

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Few studies showed that neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), total tubulin-associated unit (TAU), and ubiquitin carboxy-terminal hydrolase-L1 (UCH-L1) may be related to neurological manifestations and severity during and after SARS-CoV-2 infection. The objective of this work was to investigate the relationship among nervous system biomarkers (NfL, TAU, GFAP, and UCH-L1), biochemical parameters, and viral loads with heterogeneous outcomes in a cohort of severe COVID-19 patients admitted in Intensive Care Unit (ICU) of a university hospital. For that, 108 subjects were recruited within the first 5 days at ICU.

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The dietary exposure of six food azo-colours was assessed in a sample of pre-schoolers from Guaratuba-Paraná, Brazil. Consumption data of 323 children aged 2 to 5 years was collected through 3-day food records. Dietary exposure, is expressed by milligrams of food colour by kilogram of body weight per day, as compared to the Acceptable Daily Intake (ADI).

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  • Brazil has faced significant challenges during the COVID-19 pandemic, particularly with the emergence of a new variant that sparked a second wave of infections.
  • A study analyzed critically ill patients in Rio de Janeiro, revealing that a high percentage had comorbidities, and severe disease was linked to older age and various medical conditions.
  • Findings indicated an increase in the need for invasive respiratory support and acute hepatitis during the second wave, underscoring the importance of this research for improving clinical care and public health strategies.
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  • Chikungunya virus (CHIKV), transmitted by Aedes mosquitoes, has significantly affected Brazil since its introduction in 2013, leading to high case numbers and severe health outcomes, particularly in Ceará state.
  • An extensive study utilized genomic sequencing, vector data, and epidemiological records to analyze over 250,000 confirmed cases of chikungunya across Brazil from 2013 to 2022, identifying seven distinct epidemic waves.
  • The analysis revealed that females were more likely to be infected than males in Ceará, with a cumulative case-fatality ratio of 1.3 deaths per 1000 cases, and highlighted the recurrence of chikungunya in specific states like Ceará, Tocantins, and Pernambuco
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  • Cognitive dysfunction is commonly observed in patients recovering from COVID-19, with the exact mechanisms not fully understood.
  • Research indicates that the Spike protein of SARS-CoV-2 can affect brain function, as shown in mouse studies where infusion of this protein leads to cognitive impairment similar to post-COVID-19 syndrome.
  • Key findings highlight that TLR4 signaling plays a crucial role in memory dysfunction related to the Spike protein, suggesting it could be a target for addressing long-term cognitive issues in individuals after COVID-19.
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Melasma is a hard-to-treat hyperpigmentation disorder. Combined incorporation of kojic dipalmitate (KDP), the esterified form of kojic acid, and rosehip oil, an oil with antioxidant and skin-regenerating properties, into nanocarrier systems appears to be a suitable strategy to develop high-performance formulations. A high-energy method (Ultra-Turrax) was used to develop nanoemulsions containing up to 2 mg/mL KDP, 5% rosehip oil, and 7.

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The dietary exposure to low-calorie sweeteners (LCS) was estimated in a sample of pregnant Brazilian women. Consumption data were obtained with a 24-h Dietary Recall interview. Because of the uncertainty in assessing foods with LCS, they were classified into three scenarios to ensure inclusion of the 15 LCS allowed for use in Brazil: ranging from a less to a more conservative scenario.

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Lactoferrin (L), chitosan (C) and gellan (G) nanoparticles were produced by electrostatic complexation, aiming to enhance the antimicrobial characteristics of these compounds. Binary complexes (lactoferrin-gellan and chitosan-gellan) and ternary complexes (lactoferrin-chitosan-gellan) were studied in eight different proportions of biopolymers. The antimicrobial activity of nanoparticles against S.

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The robust determination of the threshold against fatigue crack propagation ΔKth is of paramount importance in fracture mechanics based fatigue assessment procedures. The standards ASTM E647 and ISO 12108 introduce operational definitions of ΔKth based on the crack propagation rate da/dN and suggest linear fits of logarithmic ΔK- da/dN test data to calculate ΔKth. Since these fits typically suffer from a poor representation of the actual curvature of the crack propagation curve, a method for evaluating ΔKth using a nonlinear function is proposed.

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Lactoferrin (L) and gellan gum (G) nanoparticles were produced in different biopolymer proportions through electrostatic complexation to enhance the antimicrobial properties of lactoferrin. The nanoparticles were characterized according to size, charge density, morphology and antimicrobial activity against and in two different broths to show the effect of the broth composition on the nanoparticle activity. The 9L:1G particles showed the highest positive zeta potential (+21.

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Fungi from the widely distributed genus Trichoderma are of great biotechnological interest, being currently used in a vast range of applications. Here, we report that high-molecular weight fraction (HWF) derived from Trichoderma asperelloides ethanolic extract exhibits antibiotic activity against staphylococcal biofilms. The antibacterial and anti-biofilm properties of T.

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Fragaria x ananassa Duch., popularly called strawberry, is known for its worldwide consumption and important biological activities, and these effects are related to its high concentration of anthocyanins. Pelargonidin-3-O-glucoside (P3G) is a major anthocyanin found in strawberry, and was evaluated for its anti-inflammatory action in experimental models.

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In the period of May to August of 2005, 19 ostrich's farms were visited in the semi-arid area of the Irecê, Bahia, in order to describe the ectoparasites. The African Black ostriches were reared in intensive system, and distributed for age group, in colonies, trio, couple or cráche. In each farm, after visually inspection of the ostrich, the feathers were taken in several areas of the body and were kept in plastic bags.

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