Publications by authors named "Larissa Bittencourt Carvalho"
Front Med (Lausanne)
May 2024
Article Synopsis
- Hansen's disease, commonly known as leprosy, primarily affects the skin and nervous system; however, there's a neural form without skin symptoms.
- A unique case is presented involving a patient with the neural form affecting peripheral nerves and the cervical spinal cord, which is unusual and rare.
- The case emphasizes the need for thorough investigation of leprosy even when symptoms are atypical, as prompt diagnosis and treatment can significantly mitigate neurological damage.
Front Immunol
December 2023
Article Synopsis
- Pure Neural Leprosy (PNL) is a rare form of leprosy that specifically impacts the peripheral nervous system, and its underlying mechanisms are not well understood.
- A study of 30 PNL patients revealed high rates of neural thickening, sensory symptoms, and neuropathic pain, as well as distinct cytokine profiles that differ from other leprosy forms.
- The findings suggest that cytokines like CCL-2 and IL-10 play significant roles in PNL, potentially influencing silent neuritis and overall disease understanding, highlighting the need for further research on its immunological aspects.
