Activation of pallidal H receptors induces catalepsy in Wistar rats: A regulatory role of CRF receptors.

An increased concentration of histamine was found in the globus pallidus of parkinsonian patients. The role of this abnormality in the development of parkinsonism is unclear. We examined cataleptogenic activity of histamine injected into the globus pallidus (GP); also, the role of H receptors in histamine effect was evaluated.

Histamine H receptors regulate anhedonic-like behavior in rats: Involvement of the anterior cingulate and lateral entorhinal cortices.

A decreased H receptor activity is observed in the anterior cingulate cortex (aCgCx) of depressed patients. The role of this abnormality in the development of depression-related processes is unstudied. We examined the influence of a decreased brain H receptor activity on rat behavior in the sucrose preference test.

Neuroanatomical correlates of the inhibition of tremulous jaw movements in rats by a combination of memantine and Δ -tetrahydrocannabinol.

Background And Purpose: Memantine and marijuana smoking have been found to inhibit tremor in parkinsonian patients, although the observed effects were relatively weak. The tremorolytic effects of combinations of memantine and cannabinoids have not been studied. Here, we have evaluated the anti-tremor activity of memantine, Δ -tetrahydrocannabinol (THC) given alone and of their combination.

Synergistic anticataleptic effect of imipramine and nicotine in a rotenone-induced rat model.

Rationale: Some antidepressants have been previously found to produce anti-parkinsonian effect; nicotine was known to mitigate experimental neurotoxic lesions. The anticataleptic efficacy of antidepressant-nicotine co-administration is unstudied.

Objectives: This work aimed to evaluate anticataleptic action of imipramine-nicotine combination in rotenone model.