Homocysteine enhances LDL fatty acid peroxidation, promoting microalbuminuria in type 2 diabetes.

Background: We aimed to establish the relationship between glycated haemoglobin (HbA(1c)), hypertension and microalbuminuria onset in type 2 diabetes. We also intended to ascertain the metabolic action of homocysteine on LDL fatty acids and on renal function.

Methods: The study was carried out on 200 patients with type 2 diabetes and 200 healthy subjects.