Cholinesterase inhibitors in Alzheimer's disease: efficacy in a non-selected population.

This paper presents preliminary results on the efficacy of acetyl-cholinesterase inhibitors (ChE-I) administered in a population of patients with mild-to-moderate Alzheimer's disease (AD), recruited in the context of an Italian Department of Health supported project (Progetto Cronos). The patients were followed up for a maximum of 21 months. Around 45% of the subjects responded well to the treatment (i.

Memory disturbances and temporal lobe epilepsy simulating Alzheimer's disease: a case report.

We report the case of a patient presenting with recurrent transient dyscognitive episodes and memory disturbances, simulating the clinical picture of early Alzheimer's disease (AD). Neuropsychological examination showed only episodic memory impairment without significant progression over time in the absence of any other cognitive dysfunctions; magnetic resonance imaging failed to show selective temporal atrophy. The suspicion that a nocturnal epileptic seizure had occurred arose on the basis of a clinical report of tongue biting and the findings of sharp waves over the temporal region on standard EEG.