Psychiatric effects of ephedra use: an analysis of Food and Drug Administration reports of adverse events.

Objective: As part of a synthesis of evidence regarding the efficacy and safety of ephedra, the authors describe data on psychiatric adverse events from reports submitted to the Food and Drug Administration (FDA).

Method: The authors reviewed all 1,820 adverse event reports related to dietary supplements containing herbal ephedra from FDA MedWatch files as of Sept. 30, 2001.

Effect of supplemental vitamin E for the prevention and treatment of cardiovascular disease.

Objective: To evaluate and synthesize the evidence on the effect of supplements of vitamin E on the prevention and treatment of cardiovascular disease.

Design: Systematic review of placebo-controlled randomized controlled trials; meta-analysis where justified.

Measurements And Main Results: Eighty-four eligible trials were identified.

Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis.

Context: Ephedra and ephedrine sometimes are used for weight loss or enhanced athletic performance, but the efficacy and safety of these compounds are uncertain.

Objective: To assess the efficacy and safety of ephedra and ephedrine used for weight loss and enhanced athletic performance.

Data Sources: We searched 9 databases using the terms ephedra, ephedrine, adverse effect, side effect, efficacy, effective, and toxic.