Publications by authors named "Lara Bonney"
This paper outlines the process by which a medical gamma camera can be utilised to support assessment of internal radionuclides for the public. While hospital based gamma cameras are able to detect photopeaks, they are often limited to an energy range of 40-540 keV. However, radionuclides with photopeak energies above 540 keV can still be detected as the partial collection of photon energy increases the count rate at lower energies.
View Article and Find Full Text PDFThe personalised oncology paradigm remains challenging to deliver despite technological advances in genomics-based identification of actionable variants combined with the increasing focus of drug development on these specific targets. To ensure we continue to build concerted momentum to improve outcomes across all cancer types, financial, technological and operational barriers need to be addressed. For example, complete integration and certification of the 'molecular tumour board' into 'standard of care' ensures a unified clinical decision pathway that both counteracts fragmentation and is the cornerstone of evidence-based delivery inside and outside of a research setting.
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- The study explores the use of stable barium (Ba) sources as substitutes for radioactive iodine (I) in nuclear medicine imaging, aiming to address uncertainties in calibration processes traditionally reliant on liquid radionuclide solutions.* -
- Researchers created and tested multiple traceable Ba sources within various configurations, conducting quantitative SPECT/CT imaging across several member institutions to compare the effectiveness of Ba versus I.* -
- Results indicate that, despite initial differences in calibration performance, a specific cross-calibration method allows Ba sources to effectively serve as surrogates for I, showcasing their potential in improving imaging accuracy and efficiency.*
Background: This work aimed to determine the implications of the variability in estimated glomerular filtration rate (eGFR) for the prediction of measured GFR (mGFR) for selection of sampling time-point in single-sample 99m Tc-diethylene-triamine-pentaacetate (DTPA) mGFR.
Methods: Patient studies were used to compare eGFR and mGFR ( n = 282). The eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration 2009 equation, from serum creatinine values measured in the laboratory ( n = 27) or using a point-of-care testing device ( n = 255).