Time to deterioration of patient-reported outcome endpoints in cancer clinical trials: targeted literature review and best practice recommendations.

Background: Time to deterioration (TTD) endpoints are often utilized in the analysis of patient-reported outcome (PRO) data in oncology clinical trials but different endpoint definitions and analysis frameworks exist that can impact result interpretation. This review examined the analysis, reporting and heterogeneity of TTD endpoints in the literature, the impact of analysis methods on results, and provides recommendations for future trials.

Methods: A targeted literature review of articles published between 2017 and 2022 was performed to collate TTD endpoints reported in oncology randomized controlled trials (RCTs).

The Acceptability, Engagement, and Feasibility of Mental Health Apps for Marginalized and Underserved Young People: Systematic Review and Qualitative Study.

Background: Smartphone apps may provide an opportunity to deliver mental health resources and interventions in a scalable and cost-effective manner. However, young people from marginalized and underserved groups face numerous and unique challenges to accessing, engaging with, and benefiting from these apps.

Objective: This study aims to better understand the acceptability (ie, perceived usefulness and satisfaction with an app) and feasibility (ie, the extent to which an app was successfully used) of mental health apps for underserved young people.

Evaluating the Appropriateness of Existing Health-Related Quality of Life Measures in Lichen Planus.

Introduction: Lichen planus (LP) is an inflammatory skin disorder that can present in various forms across the body, including lesions on the skin (cutaneous LP [CLP]), scalp (lichen planopilaris [LPP]) and mucosal regions (mucosal LP [MLP]). Several existing patient-reported outcome measures (PROMs) were identified for potential use in LP clinical development programs. This study aimed to assess the content validity and psychometric measurement properties of the Dermatology Life Quality Index (DLQI), Epworth Sleepiness Scale (ESS), Scalpdex and Oral Lichen Planus Symptom Severity Measure (OLPSSM) in an LP population.

Parenting Sense of Competence: Psychometrics and Invariance among a Community and an At-Risk Samples of Portuguese Parents.

Parenting sense of competence refers to parents' perception about their ability to perform the parenting role, one of the key dimensions in family dynamics. This construct is even more important in families at psychosocial risk, where the exercise of parenting can be more challenging. The Parenting Sense of Competence scale (PSOC) is a self-report measure that aims to assesses one's perceived efficacy and satisfaction with parenting.

The Brief COPE: Measurement Invariance and Psychometric Properties among Community and At-Risk Portuguese Parents.

Parenting generally brings about high internal and external demands, which can be perceived as stressful when they exceed families' resources. When faced with such stressors, parents need to deploy several adaptive strategies to successfully overcome these challenges. One of such strategies is coping, an important cognitive and behavioural skill.

Short Form of the Social Anxiety Scale for Adolescents among community and institutionalized Portuguese youths.

Social anxiety is a common issue arising in adolescence that can cause significant impairment and have detrimental consequences for development in the absence of treatment. In this study we examined the factor structure and the psychometric properties of a 12-item short form of the Portuguese-Language Social Anxiety Scale for Adolescents (SAS-A-SF). A community adolescent sample ( = 835) and a young offender sample ( = 244) completed the SAS-A, the Basic Empathy Scale and the Reactive-Proactive Aggression Questionnaire.

The Reactive-Proactive Aggression Questionnaire: Measurement Invariance and Reliability Among a School Sample of Portuguese Youths.

Aggression is an important risk factor for various forms of problem behaviors in adolescence, and research has often distinguished between reactive and proactive forms of aggression. The aim of the present study was to compare the psychometric properties (i.e.

The Brief Peer Conflict Scale: Psychometric Properties Among a Sample of Incarcerated Male Juvenile Offenders.

Aggression can be considered a multidimensional construct that influences various forms of antisocial behavior, including juvenile delinquency and conduct problems. The aim of the present study was to assess the psychometric properties of the Brief Peer Conflict Scale-20 item version (PCS-20) among a Portuguese forensic sample (N = 192) of incarcerated male juvenile offenders ( M = 16.62 years; SD = 1.

The Social Anxiety Scale for Adolescents: Measurement Invariance and Psychometric Properties Among a School Sample of Portuguese Youths.

Over the last decades there has been an increased interest in assessing social anxiety in adolescents. This study aims to validate the Social Anxiety Scale for Adolescents (SAS-A) to Portuguese youth, and to examine its invariance across gender as well as its psychometric properties. The participants were 782 Portuguese youths (371 males, 411 females), with an average age of 15.

Psychometric properties of the Socially Desirable Response Set-5 among incarcerated male and female juvenile offenders.

The main aim of the present study was to examine the psychometric properties of the Socially Desirable Response Set-5 (SDRS-5) among a forensic sample (N=324) of incarcerated male (n=221) and female (n=103) juvenile offenders. The Portuguese validation of the SDRS-5 demonstrated good psychometric properties, namely in terms of its factor structure, internal consistency, convergent validity, and discriminant validity that overall justifies its use among this population. Findings are discussed in terms of the use of the SDRS-5 with male and female juvenile offenders.

Quality of life of Portuguese and Spanish adolescents. A comparative study between natives and immigrants.

The aim of this study was to analyse differences in quality of life (QOL) between Spanish and Portuguese immigrant and native adolescents. In total, 475 native and immigrant adolescents (52% boys) from Algarve (Portugal) and Huelva (Spain), aged between 12 and 17 years old, were assessed with the KIDSCREEN-52. QOL dimensions were not related to most academic variables, with the exception of number of school failures, Financial Resources and Social Support from Peers.