Hormone use among the transgender, transvestites and non-binary population of Porto Alegre, Brazil, 2021: a cross-sectional study.

Objective: To describe the prevalence of hormone use, sociodemographic profile, and access to health services among the transgender, transvestite, and nonbinary population in Porto Alegre, capital city of Rio Grande do Sul state.

Methods: A cross-sectional study was conducted between September and November 2021, using a snowball sampling method (n=65). Data were collected through a self-administered questionnaire with transgender people aged 18 years or older.

Do girls wash dishes and boys play sports? Gender inequalities in physical activity and in the use of screen-based devices among schoolchildren from urban and rural areas in Brazil.

Objective: The aim of the study was to analyze gender inequalities in types of physical activity (PA) and in the use of screen-based devices among schoolchildren from both urban and rural areas in Brazil.

Methods: Data from two population-based surveys conducted in 2019 (urban areas: n = 2,479; 52.6% girls; age = 9.

Critical Velocity, Maximal Lactate Steady State, and Muscle MCT1 and MCT4 after Exhaustive Running in Mice.

Although the critical velocity (CV) protocol has been used to determine the aerobic capacity in rodents, there is a lack of studies that compare CV with maximal lactate steady state intensity (iMLSS) in mice. As a consequence, their physiological and molecular responses after exercise until exhaustion at CV intensity remain unclear. Thus, we aimed to compare and correlate CV with iMLSS in running mice, following different mathematical models for CV estimation.

Melaleuca alternifolia formulations in the treatment of experimental pythiosis.

Essential oils (EO) are aromatic compounds from the plant secondary metabolism. Melaleuca alternifolia EO is well known for its medicinal properties and promising use as an antimicrobial agent. Pythiosis is a difficult-to-treat and emerging disease caused by the oomycete Pythium insidiosum.

Association between baseline Mini-Mental State Examination score and dementia incidence in a cohort of oldest old.

Background: The Brazilian population has aged rapidly. The oldest old, defined as persons aged 80 years or older, is the fastest growing segment of the Brazilian population. Several instruments have been used to assess the cognitive performance of the older people and predict dementia.

Interplay between gasotransmitters and potassium is a Key factor during plant response to abiotic stress.

Carbon monoxide (CO), nitric oxide (NO) and hydrogen sulfide (HS) are gasotransmitters known for their roles in plant response to (a)biotic stresses. The crosstalk between these gasotransmitters and potassium ions (K) has received considerable attention in recent years, particularly due to the dual role of K as an essential mineral nutrient and a promoter of plant tolerance to abiotic stress. This review brings together what it is known about the interplay among NO, CO, HS and K in plants with focus on the response to high salinity.

Association between fibroblast growth factor 23 and functional capacity among independent elderly individuals.

Objective: To examine the association of between serum fibroblast growth factor 23 and the functional capacity among independent individuals, aged 80 or older.

Methods: The functional capacity of 144 elderly was assessed by Instrumental Activities of Daily Living, cognitive tests, handgrip strength and the timed ability to rise from a chair and sit down five times. Fibroblast growth factor 23 was measured using an ELISA assay.

Evaluation of the reduction of methane emission in swine and bovine manure treated with black soldier fly larvae (Hermetia illucens L.).

The study evaluates Hermetia illucens larvae's ability to decrease direct methane emissions and nutrients from cattle and swine manure. Hermetia illucens larvae were put into fresh cattle and swine manure, and the same conditions, without larvae, for the control treatment were established. The methane emissions were measured until the first prepupae appeared.

Functional capacity, renal function and vitamin D in community-dwelling oldest old.

Purpose: The aim of this study was to evaluate the association between the decline in estimated glomerular filtration rate (eGFR) and serum 25(OH)D with the physical and mental functional capacity of elderly individuals aged 80 years or older.

Methods: We evaluated the functional capacity in its multidomain aspects: Geriatric Depression Scale (GDS), Instrumental Activities of Daily Living (IADL), Mental State Mini-Exam (MMSE), Verbal Fluency Test (VF), handgrip strength and time to sit and rise from a chair five times, combined creatinine and cystatin C-based eGFR and 25(OH)D levels in 205 independent asymptomatic and community-dwelling elderly subjects in a cross-sectional study.

Results: Every 1 year of life, there was reduction of about 10% chance of adequate performance in functional capacity.

Ultrasonographic assessment of thyroid volume in oldest-old individuals.

Objective: The aim of this study was to describe the relationship between thyroid volume and age, gender, anthropometric characteristics, and echogenicity in oldest-old subjects in an iodine-sufficient area.

Subjects And Methods: The study included 81 independent elderly individuals aged ≥ 80 years (65 [80.2%] women).

Association between increased serum thyrotropin concentration and the oldest old: what do we know?

To assess studies that evaluate the relation between serum thyrotropin concentration, very old subjects, and their events. We searched the PubMed, SciELO, and LILACS databases for articles published between 2004 and 2012. Our search was restricted to studies involving humans aged 65 years or older, and written in English, Spanish, or Portuguese.

The Effect of Anchors and Training on the Reliability of Voice Quality Ratings for Different Types of Speech Stimuli.

Objective: The main objective of the present study was to investigate if the type of voice stimuli-sustained vowel, oral reading, and connected speech-results in good intrarater and interrater agreement/reliability.

Study Design: A short-term panel study was performed.

Methods: Voice samples from 30 native European Portuguese speakers were used in the present study.

Estimation of glomerular filtration rate from serum creatinine and cystatin C in octogenarians and nonagenarians.

Background: Equations to estimate GFR have not been well validated in the elderly and may misclassify persons with chronic kidney disease (CKD). We measured GFR and compared the performance of the Modification of Diet in Renal Disease (MDRD), the Chronic Kidney Disease-Epidemiology Collaboration (CKD-Epi) and the Berlin Initiative Study (BIS) equations based on creatinine and/or cystatin C in octogenarians and nonagenarians.

Methods: Using cross-sectional analysis we assessed 95 very elderly persons (mean 85 years) living in the community.

Characterization of hip passive stiffness of volleyball, basketball and futsal young athletes.

Objectives: (1) To establish the reference values of the test of 'Position of hip passive resistance against gravity' (PHPR) in young athletes; (2) To investigate differences between the values of PHPR test according to athlete's sex, age and sport practiced.

Design: Cross-sectional.

Setting: Sports club.

The importance of HDL-C and CRP in cardiovascular risk evaluation in longevous elderly individuals.

The association between total mortality, lipoproteinS, and inflammatory markers, and their implications with aging and longevity are often controversial. Among the most often studied markers are low HDL cholesterol and high C-reactive protein. Particularly in octogenarians, it is expected that the impact of the inclusion of HDL cholesterol and C-reactive protein will improve the stratification of absolute cardiovascular risk.

APOA4 polymorphism as a risk factor for unfavorable lipid serum profile and depression: a cross-sectional study.

Introduction: APOA1/C3/A4/A5 gene cluster is closely involved in lipid metabolism, and its polymorphisms have been associated with coronary heart disease and lipid plasma levels. Here, we aimed to investigate associations of APOC3 (3238C>G, -482C>T, 1100C>T) and APOA4 (Gln360His, Thr347Ser) polymorphisms in 382 individuals from a cohort of a Longitudinal Brazilian Elderly Study with major age-related morbidities and with lipid and protein serum levels.

Materials And Methods: The whole sample was genotyped by polymerase chain reaction-restriction fragment length polymorphism.

APOA1/A5 variants and haplotypes as a risk factor for obesity and better lipid profiles in a Brazilian Elderly Cohort.

Genetic variations in the APOA1/C3/A4/A5 gene cluster have been studied and proposed to be the leading key for susceptibility to cardiovascular diseases and age-associated disorders. We aimed to investigate the associations of rs12721026 (APOA1) and rs1729408 (APOA5) polymorphisms and their haplotypes with some age-related diseases, as well as with lipids and proteins serum levels in a cohort from a Brazilian Elderly Longitudinal Study (EPIDOSO). Genotyping was performed by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP).

Association of PPARalpha gene polymorphisms and lipid serum levels in a Brazilian elderly population.

Peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear transcription factor strictly involved in lipid and lipoprotein metabolisms. Thus, PPARalpha gene polymorphisms have been investigated as cardiovascular risk factors. We aimed to investigate associations of L162V and intron 7G>C polymorphisms with common morbidities affecting a Brazilian elderly cohort as well as with lipid and protein serum levels.

Apolipoprotein A1 gene polymorphisms as risk factors for hypertension and obesity.

Several polymorphisms in apolipoprotein A1 (APOA1) gene have been associated with metabolic diseases. Increased transcription efficiency was observed in -75A allele carriers compared to -75G allele homozygotes. +83C allele was associated with higher body mass index and waist-to-hip ratio in type II diabetes subjects.

Epidemiology and burden of herpes zoster and post-herpetic neuralgia in Australia, Asia and South America.

Following the development of a herpes zoster vaccine and the successful introduction of widespread varicella vaccination in the USA, many countries are considering similar vaccination programmes. However, before implementing such programmes, it is important to describe the regional baselines of varicella and herpes zoster epidemiology, both to aid the design of vaccination strategies and to observe trends after the introduction of vaccination. In many areas of the world, this information is difficult to gather, and the epidemiology of herpes zoster and post-herpetic neuralgia in these regions is poorly understood.

[Prevalence of vitamin D deficiency, insufficiency and secondary hyperparathyroidism in the elderly inpatients and living in the community of the city of São Paulo, Brazil].

The occurrence of osteoporotic fractures in the elderly is associated with reduced levels of vitamin D and resulting secondary hyperparathyroidism, and inpatients are the ones at a higher risk. In Brazil, given its high level of insolation, the populations large amount of vitamin D is inferred to be adequate. In this study we aimed to assess the serum levels of 25-hydroxivitamin D (25OHD), parathormone (PTH) and ionized calcium (Cai), as well as to analyze the prevalence of both hypovitaminosis D and secondary hyperparathyroidism in the elderly living in the city of São Paulo.

Association of lipase lipoprotein polymorphisms with myocardial infarction and lipid levels.

Background: Lipoprotein lipase has an important role in lipid metabolism. Elevated levels of very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) are associated with increased risk of coronary artery disease and low levels of high-density lipoprotein (HDL) are potentially atherogenic. The HindIII and S447X polymorphisms of the lipoprotein lipase (LPL) gene are associated with cardiovascular disease in some populations.

APO A-V-1131T-->C polymorphism frequency and its association with morbidity in a Brazilian elderly population.

Identification of genetic polymorphisms as risk factors for complex diseases affecting older people can be relevant for their prevention, diagnosis and management. The -1131T-->C polymorphism of the apolipoprotein A-V gene (APO A-V) is tightly linked to lipid metabolism and has been associated with increased triglyceride levels and familial dyslipidemia. The aims of this study were to analyze the allele and genotype frequencies of this polymorphism in a Brazilian elderly population and to investigate any association between the polymorphism and major morbidities affecting elderly people.