Effect of intra-alveolar delivery of Frondoside A on inflammatory response of delayed tooth replantation.

Background/aim: Frondoside A is a sea cucumber extract which is well known for its anti-inflammatory and immunomodulatory properties. The purpose of this study was to evaluate the effect of Frondoside A application in the alveolar socket on inflammatory responses after delayed replantation in rat teeth.

Materials And Methods: Human periodontal ligament cells were cultured and exposed to Frondoside A.