Publications by authors named "Laptin Ho"
Tissue injuries, including burns, are major causes of death and morbidity worldwide. These injuries result in the release of intracellular molecules and subsequent inflammatory reactions, changing the tissues' chemical milieu and leading to the development of persistent pain through activating pain-sensing primary sensory neurons. However, the majority of pain-inducing agents in injured tissues are unknown.
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- - This study examined the outcomes of 940 critically ill patients with tuberculosis (TB) admitted to ICUs in Hong Kong over an 11-year period, finding high mortality rates of 24.7% in ICUs and 41.1% in hospitals, with a significant portion of ICU deaths occurring in patients who did not receive TB treatment.
- - Researchers used methods like generalized linear modeling and analyzed mortality trends, concluding that delays in TB treatment are linked to increased hospital mortality, and they noted that diagnostic methods like MTB PCR were underutilized.
- - The results suggest that despite TB being preventable and treatable, survival rates for ICU patients have not improved, emphasizing the need for quicker diagnoses and treatment to enhance patient
Background: Early intensive care unit (ICU) protocolized rehabilitative programs have been described previously, yet with differing starting time points and mostly on mechanically ventilated patients. We extended the concept to all admitted ICU patients and investigate the efficacy of early mobilization in improving mobility of the critically ill, address issues surrounding the timing and intensity of an early rehabilitative program.
Methods: Prospective cohorts of patients admitted consecutively before-and-after (control, n=92; intervention, n=90) the introduction of an early mobilization program in a single center, general hospital ICU.
Burn injuries constitute one of the most serious accidental injuries. Increased metabolic rate is a hallmark feature of burn injury. Visualising lactate dehydrogenase (LDH) activity has been previously used to identify metabolic activity differences, hence cell viability and burn depth in burn skin.
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