Publications by authors named "Lappo V"

The paper deals with laser mass spectrometric determination of elements from the materials to be implanted into the animal organs by using the sieve endoprostheses made of titanium nickelide.

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Laser mass spectrometric analysis of a biomedical sample was made on exposure to laser radiation at lambda 2 = 532 nm. The parameters of laser radiation and mass spectra were comparatively analyzed by using the basic and second harmonics of aluminum-yttrium-garnet-based laser. The sensitivity of laser mass spectrometry of biomedical samples is increased.

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Migration of dioctyl phthalate from the polyvinyl chloride containers (PVC-containers) into blood, its components, preservatives and infusion solutions was studied for the purpose of estimating toxicity of the articles. Dependence of the plasticizer cumulation on the composition of the media found in the containers was discovered. The effect of the storage conditions on the toxicological and hygienic characteristics of the containers and intact condition of the bioproducts housed therein was investigated.

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The main tendencies in the development of methods for hemo- and lymphosorption are considered. Base toxicological requirements to sorbents have been formulated. Special attention is paid to possible tox effects of sorbents containing carcinogenic admixtures.

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The possibility of quantitative prognosis of chemical compounds and complex mixtures toxicity by means of a biotechnical system with suspension of bull spermatozoa sensor was investigated. The concentration of some chemical compounds, inhibiting by half spermatozoa motility has been experimentally determined. A correlation between the values determined and acute toxicity of the compounds tested has been established.

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This paper discusses the results of experiments conducted with a view to determining the hidden effects of epoxy composites, which cannot generally be ascertained through the use of various toxicological, biochemical, immunological, allergic, morphological, and cytological methods of examination. To discover possible hidden effects of epoxy filling materials experimental use was made of the following methods: hunger diet, ethylalcohol supply, and composite extract supply. Shifts in functions of the organism were evaluated by the following criteria: weight dynamics of animals, histamine content of the blood, and eosinopenic reaction of the blood.

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