[Nurse's evaluation of patients' problems as a methodological component in improvement of the quality of nursing care].

Nurse's diagnosis is an integral part of nursing process. Currently used methods within the framework of nursing process do not fully meet the requirements to each discipline. The authors discuss an approach to nurse's diagnosis, which will create prerequisites for developing a principally new standard approach to nurse's participation from a modern viewpoint.

[Modified method of assessing spontaneous erythrocyte aggregation].

To prevent infection of the examinees via blood during venipuncture and to simplify the method for assessment of red cell spontaneous aggregation the authors have compared red cell aggregation in venous and capillary blood. Red cell aggregation coefficients assessed by various methods in blood samples collected from the finger and vein were virtually the same; hence, this characteristics can be investigated in a capillary blood sample.

[The role of the system of hemostasis in the development of vascular lesions in diabetes mellitus].

The examination of 179 patients with diabetes mellitus has shown that the mechanisms of vascular wall damage and changes in the system of hemostasis are different in type I and II diabetes mellitus. In type I diabetes mellitus vascular wall damages are associated with carbohydrate metabolic derangements, changes in the platelet link of hemostasis and blood coagulation system. In type II diabetes mellitus vascular wall damages are associated with lipid metabolic derangements and changes in the erythrocytic link of hemostasis.

[Characteristics of the changes in microcirculatory hemostasis in patients with exercise-induced stenocardia].

In patients with angina of effort all links in the system of microcirculatory hemostasis are activated and closely interconnected. Changes in one and the same index could be compensatory and pathological and it should be taken into account in attempts to interfere in the system of hemostasis. Lipid metabolic derangement in patients with angina of effort should be regarded as one of the most unfavorable factors in a course of disease.

[Electron microscopic, histochemical and functional assessment of the effect of aspirin on the thrombocytes of healthy persons and ischemic heart disease patients].

Electron microscopical and electron histochemical studies and functional investigation of platelets have been undertaken in 10 normal individuals and 20 patients with ischaemic heart disease and angina pectoris of effort before and after acetylsalicylic acid (ASA) administration during 3 days. In ischaemic heart disease changes in the ultrastructure of platelets have been recorded, pointing to their activation. After ASA administration there was decrease of functional activity, due to structural changes in the plasma membrane, lysosome membranes, fragmentation of platelets, enhanced process of autophagia, decrease of enzymatic activity of structure organelles of platelets.