CRUSE -An innovative mobile application for patient monitoring and management in chronic spontaneous urticaria.

Background: Chronic spontaneous urticaria (CSU) is unpredictable and can severely impair patients' quality of life. Patients with CSU need a convenient, user-friendly platform to complete patient-reported outcome measures (PROMs) on their mobile devices. CRUSE , the Chronic Urticaria Self Evaluation app, aims to address this unmet need.

[The Normative Legal Base of Providing Quality of Security of Medical Activities].

The article substantiates the actuality of legal normative support of maintenance of quality of medical activities. The analysis is presented concerning actual normative legal base in the Russian Federation regulating control of volumes, terms, quality and conditions of medical care provision. The evaluation is given concerning actual executive orders of Minzdrav of Russia regulating quality of medical care.

Study of inelastic nuclear interactions of 400 GeV/c protons in bent silicon crystals for beam steering purposes.

Inelastic nuclear interaction probability of 400 GeV/c protons interacting with bent silicon crystals was investigated, in particular for both types of crystals installed at the CERN Large Hadron Collider for beam collimation purposes. In comparison to amorphous scattering interaction, in planar channeling this probability is for the quasi-mosaic type (planes (111)), and for the strip type (planes (110)). Moreover, the absolute inelastic nuclear interaction probability in the axial channeling orientation, along the axis, was estimated for the first time, finding a value of for a crystal 2 mm long along the beam direction, with a bending angle of 55 rad.

Observation of multiple volume reflection of ultrarelativistic protons by a sequence of several bent silicon crystals.

The interactions of 400 GeV protons with different sequences of bent silicon crystals have been investigated at the H8 beam line of the CERN Super Proton Synchrotron. The multiple volume reflection of the proton beam has been studied in detail on a five-crystal reflector measuring an angular beam deflection theta = 52.96 +/- 0.

Volume reflection dependence of 400 GeV/c protons on the bent crystal curvature.

The trend of volume reflection parameters (deflection angle and efficiency) in a bent (110) silicon crystal has been investigated as a function of the crystal curvature with 400 GeV/c protons on the H8 beam line at the CERN Super Proton Synchrotron. This Letter describes the analysis performed at six different curvatures showing that the optimal radius for volume reflection is approximately 10 times greater than the critical radius for channeling. A strong scattering of the beam by the planar potential is also observed for a bend radius close to the critical one.

High-efficiency deflection of high-energy protons through axial channeling in a bent crystal.

Beam deflection due to axial channeling in a silicon crystal bent along the 111 axis was observed with 400 GeV/c protons at the CERN Super Proton Synchrotron. The condition for doughnut scattering of protons by the atomic strings of the crystal was attained. Such a condition allowed one to observe a beam deflection of 50 murad with about 30% efficiency.

Apparatus to study crystal channeling and volume reflection phenomena at the SPS H8 beamline.

A high performance apparatus has been designed and built by the H8-RD22 collaboration for the study of channeling and volume reflection phenomena in the interaction of 400 GeV/c protons with bent silicon crystals, during the 2006 data taking in the external beamline H8 of the CERN SPS. High-quality silicon short crystals were bent by either anticlastic or quasimosaic effects. Alignment with the highly parallel (8 murad divergence) proton beam was guaranteed through a submicroradian goniometric system equipped with both rotational and translational stages.

Volume reflection of a proton beam in a bent crystal.

Volume reflection predicted in the mid-1980s by Taratin and Vorobiev has been observed for the first time in the interactions of a 70 GeV proton beam with a short bent crystal. Incident protons deviate from convex atomic planes in the bulk of the crystal as a result of coherent interaction with bent lattice around the tangency point of particle trajectory with a curved atomic plane. The deflection angle 2theta(R) was found to be (39.

[An efficiency study of transplantation of allogenic fibroblasts cultivated in collagen gel for the treatment of corneal burn defects in experiment].

The paper contains the results of using a mew method applicable to regulation of corneal regeneration, i.e. transplantation of allogenic fibroblasts cultivated in collagen gel within an experimental model of acute alkali corneal burns in rabbits.

[Significance of the study of the pachymetric index in the evaluation of the process of eye adaptation to contact lenses].

The authors have examined the thickness of the cornea in 270 patients with weak and moderate myopia during adaptation of the eye to soft or rigid contact lenses. They have revealed a linear correlation between the period of wearing the lens and the degree of the pachometric index change during adaptation of the eye to contact lenses. The maximum permissible period for daily wearing of contact lenses have been determined, not involving essential shifts in water-salt metabolism of the cornea.

[Changes in the RNA content of the blood plasma in rats with Ehrlich ascitic cancer].

The RNA content in the blood plasma of tumour-bearing animals correlates with the tumour growth stage. The development of Ehrlich carcinoma in rats is followed by the RNA increase in the blood plasma, while spontaneous regression of the tumour is accompanied by a decrease of the RNA content in the blood plasma of rats with Ehrlich carcinoma almost to the normal level. The fractional spectrum of the blood plasma RNA in the tumour bearing rats is similar to that of the cell-free ascitic fluid of rats.

[Characteristics of nucleic acid secreted by Ehrlich ascites carcinoma cells].

Cells of Ehrlich ascite tumour secrete RNA to the medium. By ultracentrifugation within the gradient of cesium sulphate density the extracellular heterogenic RNA was found to contain the RNA-DNA hybrids. It is suggested that RNA secreted by the tumour cells participates in the tumour-host interactions.

Polymorphism of human blood groups and incidence of influenza A/Hong Kong (H3N2).

During three epidemics of influenza A/Hong Kong (H3N2) and experimentally in vaccines, the relation between influenza infection and ABo, Rh and MN blood groups was studied. Examinations of 2760 patients with laboratory-confirmed diagnosis of influenza and 749 persons vaccinated with live influenza vaccine showed that individuals of blood groups O and B were susceptible to influenza 1.67 and 1.