Optimizing diagnosis and surgical decisions for chronic osteomyelitis through radiomics in the precision medicine era.

Chronic osteomyelitis is a complex clinical condition that is associated with a high recurrence rate. Traditional surgical interventions often face challenges in achieving a balance between thorough debridement and managing resultant bone defects. Radiomics is an emerging technique that extracts quantitative features from medical images to reveal pathological information imperceptible to the naked eye.

Evaluating the clinical performance of methylation for colorectal cancer detection.

The performance and clinical accuracy of combined methylation were evaluated in diagnosing colorectal cancer (CRC) and advanced adenoma.  A total of 2333 participants were enrolled to assess the sensitivity and specificity of biomarkers in diagnosing CRC in a multicenter clinical trial through feces DNA methylation tests. methylation showed excellent performance for CRC detection in biomarker research and the real world.