Publications by authors named "Lanping Pi"

Article Synopsis
  • Infected bone defects (IBDs) create major challenges for orthopedic surgeons due to their economic and psychological impact, necessitating the development of better treatment options.
  • Tantalum (Ta) is a promising material for orthopedic implants because of its biocompatibility and corrosion resistance, but it needs functionalization to enhance antibacterial properties for IBD management.
  • The review discusses recent advancements in modifying Ta scaffolds for improved antibacterial functionality, highlighting various methods used to enhance their effectiveness in treating IBDs.
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Bacterial infections can compromise the physical and biological functionalities of humans and pose a huge economical and psychological burden on infected patients. Nitric oxide (NO) is a broad-spectrum antimicrobial agent, whose mechanism of action is not affected by bacterial resistance. S-nitrosoglutathione (GSNO), an endogenous donor and carrier of NO, has gained increasing attention because of its potent antibacterial activity and efficient biocompatibility.

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