Publications by authors named "Lanlan Wu"

Background: Evidence regarding the C-reactive protein‒albumin‒lymphocyte (CALLY) index and mortality risk in individuals with cardiovascular disease (CVD) is scarce. This study investigated the relationships of the CALLY index with all-cause and cardiovascular mortality risk in CVD patients among American adults.

Methods: This study enrolled 2183 CVD individuals from five NHANES cycles (2001-2010), and mortality outcomes were determined by linking the data to National Death Index (NDI) records up to December 31, 2019.

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NiFe-based materials are widely utilized as anode electrocatalysts for the oxygen evolution reaction (OER) in anion exchange membrane water electrolyzers (AEMWE). However, their performance under actual fluctuating power supply remains poorly understood. In this study, the OER performance and degradation mechanisms of various NiFe-based OER catalysts are investigated in AEMWE under both constant and fluctuating voltage conditions.

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Background: Tryptanthrin (Couroupitine A) is isolated from indigo-bearing traditional Chinese herbal medicines. It has a broad spectrum of pharmacological and biological activities. However, the potential effects of tryptanthrin on platelet function and thrombus formation remain elusive.

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Background: Metabolic syndrome (MetS) is a global public health problem that significantly impacts human health and quality of life. The relationship between MetS and the C-reactive protein-albumin-lymphocyte (CALLY) index is uncertain.

Methods: This study analyzed the data of 7,534 individuals from the National Health and Nutrition Examination Survey cycles (2003-2010 cycles).

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This study analyzed dipeptidyl peptidase-IV (DPP-IV) inhibitory peptides from Tartary buckwheat (Fagopyrum tataricum) protein hydrolysates, known for managing chronic diseases. Simulated gastrointestinal digestion enhanced the inhibitory activity of DPP-IV. Using anion-exchange resin DEAE-52, reverse high-performance liquid chromatography, and LC-MS/MS, eight novel peptides were identified.

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Cytoskeletal remodeling and mitochondrial bioenergetics play important roles in thrombocytopoiesis and platelet function. Recently, α-actinin-1 mutations have been reported in patients with congenital macrothrombocytopenia. However, the role and underlying mechanism of α-actinin-1 in thrombocytopoiesis and platelet function remain elusive.

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The cardiovascular kidney metabolic (CKM) syndrome is a dynamic geriatric condition that has received limited research attention regarding its potential associations with the triglyceride glucose (TyG) index. This study aims to explore the potential association between the TyG index and advanced CKM syndrome. Data for this cross-sectional study were obtained from the National Health and Nutrition Examination Survey (NHANES) conducted between 2011 and 2018.

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Tartary buckwheat, a protein-rich pseudocereal with anti-diabetic effects, has not yet been fully explored as a source of dipeptidyl peptidase-IV (DPP-IV) inhibitory peptides. This study aims to discover novel DPP-IV inhibitory peptides from tartary buckwheat protein (TBP). Five hydrolysis methods were employed, with simulated gastrointestinal digestion (SGID) releasing the most active DPP-IV inhibitory hydrolysates, showing both the highest degree of hydrolysis (22.

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Article Synopsis
  • The study examined how different steaming durations (0, 4, 8, and 12 hours) affect the structure and characteristics of polysaccharides (PCPs), particularly regarding digestion, absorption, and gut microbiota fermentation.
  • Chemical analysis revealed that longer steaming reduced carbohydrate content while increasing certain components like uronic acid and protein in the PCPs.
  • Results showed that while all PCPs were resistant to saliva digestion, they improved gastrointestinal digestibility and altered gut microbiota composition, leading to increased short-chain fatty acid production, though this declined with longer steaming times.
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We were to explore the effect of Bixie combined with perioperative multimodal analgesia management on postoperative pain and wound healing of mixed hemorrhoids. A total of 240 patients with mixed hemorrhoids in this hospital from June 2022 to September 2023 were chosen, with 120 in the control group receiving perioperative multimodal analgesia management and 120 in the observation group receiving Bixie combined with perioperative multimodal analgesia management. The results showed that compared with the control group, the observation group had lower visual analogue scale (VAS) scores at 1, 3, 5 and 7 days after the surgery; the 5-hydroxytryptamine (5-HT), prostaglandin E2 (PGE2), nitric oxide (NO), interleukin-2 (IL-2), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) of the observation group at 24 hours and 72 hours after the surgery were lower; the vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), platelet-derived growth factor (PDGF) and wound healing rate of the observation group at 7 days after the surgery were higher; the total effective rate of the observation group was higher.

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The core goal of feature matching is to establish correspondences between two images. Current methods without detectors achieve impressive results but often focus on global features, neglecting regions with subtle textures and resulting in fewer matches in areas with weak textures. This paper proposes a feature-matching method based on local window aggregation, which balances global features and local texture variations for more accurate matches, especially in weak-texture regions.

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Image encryption is crucial for protecting image privacy and ensuring security. Encrypting large batches of images of different types and sizes simultaneously with losslessly decryption is often necessary. This paper proposes an optical asymmetric multi-image encryption algorithm to meet these demands.

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Background: The association of BCAAs (isoleucine, leucine, and valine) with cardiovascular and cerebrovascular diseases has been widely recognized by researchers, but there is limited evidence to support the relationship between BCAAs and multiple chronic conditions (MCCs) in older adults. This study aimed to explore the correlation between BCAA levels in the diets of older adults and MCCs.

Methods: Based on a health management cohort project in Nanshan District of Shenzhen, 4278 individuals over 65 years old were selected as participants via multi-stage stratified sampling from May 2018 to December 2019.

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Article Synopsis
  • - Nickel anchored N-doped carbon electrocatalysts (Ni-N-C) are being developed for efficient electrochemical reduction of carbon dioxide (CORR), but their optimal design is unclear due to a lack of understanding of the structure-activity relationship.
  • - Research indicates that the amount of pyridinic nitrogen in Ni-N-C significantly influences its CORR activity, showing a positive correlation between pyridinic-N content and performance.
  • - The study highlights that Ni-N-C with the highest pyridinic-N content, sourced from ammonia, achieves excellent CORR performance with a carbon monoxide faradaic efficiency of 99.8%, paving the way for efficient and low-cost electrocatalysts.
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Article Synopsis
  • Age-related changes in testicular function can lead to health issues, particularly highlighted by late-onset hypogonadism (LOH), which is not fully understood.
  • Research using single-cell RNA sequencing has identified Sertoli cells as key players in the metabolic processes within the testes, showing that older Sertoli cells struggle with waste management and become inflamed.
  • A high-fat diet was found to mimic the effects of LOH in mice, but restoring lysosomal function improved testosterone levels, suggesting that targeting Sertoli cell health could offer new treatment options for LOH.
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Background: Nanoplastics (NPs) are now a new class of pollutants widely present in the soil, atmosphere, freshwater and marine environments. Nanoplastics can rapidly penetrate cell membranes and accumulate in human tissues and organs, thus posing a potential threat to human health. The heart is the main power source of the body.

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Oxygen evolution reaction (OER) plays a key role in electrochemical conversion, which needs efficient and economical electrocatalyst to boost its kinetics for large-scale application. Herein, a bimetallic CoP/FePheterostructure with a three-dimensional ordered macroporous structure (3DOM-CoP/FeP) was synthesized as an OER catalyst to demonstrate a heterogeneous engineering induction strategy. By adjusting the electron distribution and producing a lot of active sites, the heterogeneous interface enhances catalytic performance.

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Faced with the pollution caused by particulate matter (PM) in the air, the prevalence of infectious diseases, and the environmental burden by use of nondegradable polymers, the existing filter materials such as meltblown cloth of polypropylene cannot satisfactorily meet people's requirements. In this study, Ag nanoparticles were loaded onto ZIF-8 particles by impregnation reduction to prepare the positively charged Ag@ZIF-8. The porous fibrous membranes of Ag@ZIF-8 with polylactide (PLA) were manufactured by electrostatic spinning technology.

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The development of highly active and durable nonprecious metal-based bifunctional electrocatalysts for oxygen reduction/evolution reaction (ORR/OER) is important for rechargeable zinc-air batteries. Herein, a three-dimensional conductive niobium-doped TiO-TiO heterostructure supported ZIF-67-derived Co-NC bifunctional catalyst was fabricated. In the Co-NC@Nb-TiO catalyst, the Nb doping promoted the formation of TiO-TiO heterojunction support, enhanced its conductivity and stability and provided strong electron metal-support interaction between Co-NC and Nb-TiO.

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As an attractive high-energy-density technology, the practical application of lithium-sulfur (Li-S) batteries is severely limited by the notorious dissolution and shuttle effect of lithium polysulfides (LiPS), resulting in sluggish reaction kinetics and uncontrollable dendritic Li growth. Herein, a p-n typed heterostructure consisting of n-type MoS nanoflowers embedded with p-type NiO nanoparticles is designed on carbon nanofibers (denoted as NiO-MoS @CNFs) as both cathode sulfur immobilizer and anode Li stabilizer for practical Li-S batteries. Such p-n typed heterostructure is proposed to establish the built-in electric field across the heterointerface for facilitated the positive charge to reach the surface of NiO-MoS , meanwhile inherits the excellent LiPS adsorption ability of p-type NiO nanoparticles and catalytic ability of n-type MoS .

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Background: Weight loss was supposed to help with decreasing risk of premature mortality. However, results on this topic remain debatable and limited by study design.

Objective: The present study aimed to investigate the association between weight loss and all-cause mortality among US adults with overweight or obesity in a national cohort study by using propensity score matching (PSM) analysis.

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Objective: This study evaluated the associations of serum ferritin (SF) concentration during pregnancy with the risk of adverse maternal and fetal pregnancy outcomes.

Methods: We conducted a retrospective study of 2327 pregnant women from 2015 to 2020 in Guangdong, China. SF concentrations were measured at 16-18th and 28-32th week of gestation.

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Background: In recent years, results on the association between serum uric acid (UA) and pregnancy outcomes have been inconsistent, and the association between urea nitrogen (UN) and adverse pregnancy outcomes in normal pregnant women has not been reported. Thus, we examined the association of UA and UN levels during gestation with the risk of adverse pregnancy outcomes in a relatively large population.

Methods: A total of 1602 singleton mothers from Union Shenzhen Hospital of Huazhong University of Science and Technology at January 2015 to December 2018 were included.

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Gestational Diabetes Mellitus (GDM) has an effect on the health of pregnant women and fetuses. Procyanidins (PA) is a flavonoid with anti-diabetic activity, but its effects and mechanisms on GDM have not been defined. Herein, we studied further the functions and mechanisms of PA on insulin resistance (IR) in GDM mice, as well as on postpartum and offspring mice.

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