The synergistic effect of thermodynamic promoter tetrafluoroethane (R134a) and kinetic promoter sodium dodecyl sulfate (SDS) can significantly improve the phase equilibrium conditions required for CO hydrate formation and promote rapid generation of CO hydrate. Based on this, this study investigates the influence of SDS and R134a synergy on the separation of CO/H mixed gas using the hydrate method. The research reveals that without SDS addition, R134a hydrate forms first at the gas-liquid interface before CO hydrate induction, hindering gas-liquid exchange.
View Article and Find Full Text PDFThe conquest of land by plants was concomitant with, and possibly enabled by, the evolution of three-dimensional (3D) growth. The moss Physcomitrium patens provides a model system for elucidating molecular mechanisms in the initiation of 3D growth. Here, we investigate whether the phytohormone ethylene, which is believed to have been a signal before land plant emergence, plays a role in 3D growth regulation in P.
View Article and Find Full Text PDFObjective: This study aimed to investigate the expression of T helper 1 (Th1)/Th2/Th17- related cytokines and human beta defensins 2 and 3 (hBD-2 and -3) in the saliva of patients with erosive oral lichen planus (EOLP) and to explore their role in the pathogenesis of EOLP and the effects of glucocorticoids on EOLP.
Methods: A total of 30 patients with EOLP and 20 age- and sex-matched healthy individuals were included in this study. The patients were treated with prednisone at a dose of 0.
Electric fields have been proven to be capable of significantly affecting the equilibrium state of hydrates. In this study, the thermodynamic properties and structural changes of methane hydrate (MH) in various anion solutions in an electric field at 0.7 V/nm were investigated by molecular dynamics simulations.
View Article and Find Full Text PDFIntroduction: Allergen-specific IgE (sIgE) sensitization exists in a considerable fraction of chronic spontaneous urticaria (CSU) patients. Basophils have been implicated in the pathogenesis of CSU. This paper aimed to explore the relationship between allergic sensitization and basophil reactivity in CSU and the possible underlying mechanism.
View Article and Find Full Text PDFf. Ku is a variety of , with two known genotypes: Wuci 1 and Wuci 2. The lack of prickle on the peel of f.
View Article and Find Full Text PDFBackground: The combination of botulinum toxin type A (BoNT/A) and energy equipment have been widely used in the clinic.
Aims: To determine whether the energy of microneedle fractional radiofrequency (MFR) affects the efficacy of BoNT/A and to provide an optimal strategy for the energy device in combination with BoNT/A in the clinic.
Methods: First, a total of 45 females with moderate-to-severe periorbital crow's feet wrinkles were enrolled and divided into three groups according to different treatment methods and intervals, including BoNT/A injection alone, BoNT/A injected immediately after MFR treatment and BoNT/A injected 7 days after MFR treatment.
Natural gas hydrate, a potential energy resource, is attracting worldwide attention. In this study, we propose a new method of hydrate dissociation which uses seawater and electrostatic fields (SE method) cooperatively. The hydrate molecular dissociation mechanism of gas hydrate is a key issue in studying the kinetic properties of gas hydrate using the SE method.
View Article and Find Full Text PDFBackground: Burning mouth syndrome (BMS) is characterised by persisting burning pain of the oral mucosa, and its etiopathogenesis remains poorly understood.
Objectives: Our study aimed to detect the expression of miRNA-206 in the blood and clarify the relationship among miRNA-206, pain, anxiety and depression of BMS patients.
Methods: Thirty patients with BMS and 30 healthy individuals were enrolled in the experimental and control groups, respectively.
Type 2 diabetes mellitus (T2DM) and periodontitis are common and interrelated diseases, resulting in altered host response microbiota. The subgingival micro-organisms play a key role in periodontitis pathogenesis. To assess the shift of subgingival microbiome and metabolome in T2DM, we performed an analysis of the subgingival microbiome in patients with T2DM ( = 20) compared with non-diabetes (ND) subjects ( = 21).
View Article and Find Full Text PDFPlant Signal Behav
December 2022
Plant glutamate receptor homologs (GLRs), which function as key calcium channels, play pivotal roles in various developmental processes as well as stress responses. The moss , a representative of the earliest land plant lineage, possess multiple pathways of hormone signaling for coordinating growth and adaptation responses. However, it is not clear whether GLRs are connected to hormone-mediated growth control in the moss.
View Article and Find Full Text PDFNano-AlO particles and graphene oxide (GO) nanosheets were modified by 3-aminopropyltriethoxysilane (KH550), and then dispersed in epoxy resin, and finally modified-AlO/epoxy, modified-GO/epoxy and modified-AlO@GO/epoxy composite coatings were prepared on steel sheets by the scraping stick method. The microstructure, phase identification, surface bonding and composition of the nanoparticles were characterized by SEM, XRD, FT-IR, and Raman spectroscopy, respectively. The hardness of the coating was assessed by the pencil hardness method.
View Article and Find Full Text PDFTratt. is a specific fruit with high nutritional value and antioxidative activities. However, the key metabolites and their biosynthesis are still unknown.
View Article and Find Full Text PDFBackground: The number of people with diabetes is increasing, and many patients have significantly impaired cognitive function. For patients with diabetic encephalopathy (DE), simply lowering blood sugar does not improve learning and memory. Studies have shown that β-asarone can significantly improve cognitive impairment in patients with DE, but the specific mechanism of action is unclear.
View Article and Find Full Text PDFComput Intell Neurosci
May 2022
In this paper, an in-depth study of cross-media semantic matching and user adaptive satisfaction analysis model is carried out based on the convolutional neural network. Based on the existing convolutional neural network, this paper uses rich information. The spatial correlation of cross-media semantic matching further improves the classification accuracy of hyperspectral images and reduces the classification time under user adaptive satisfaction complexity.
View Article and Find Full Text PDFThis paper presents an in-depth study and analysis of students' role perceptions and their tendencies in classroom education using a visual inspection approach. A multi example learning student engagement assessment method based on a one-dimensional convolutional neural network is proposed. Based on the conceptual composition of student engagement, head posture, eye gaze, and eye-opening and closing states and the most used facial movement units are used as visual features.
View Article and Find Full Text PDFAims: To investigate the association between metformin and bone mineral density (BMD) in a large cohort of Chinese patients with type 2 diabetes mellitus (T2DM).
Methods: A total of 11,458 T2DM patients aged ≥40 years were included. Information on demographic, anthropometric and clinical characteristics was collected from medical records.
The fruits of () Tratt., which are rich in bioactive compounds, provide numerous health benefits, yet the overall metabolism of fruits and the metabolic profiles among different genotypes of fruits are not fully understood. In the research, we used ultra-performance liquid chromatography/tandem mass spectrometry analysis to identify and quantify metabolites including phenolic acids, amino acids, and organic acids in six genotypes; a total of 723 metabolites were identified.
View Article and Find Full Text PDFBackground And Aims: To compare the effects of real-time and retrospective flash glucose monitoring (FGM) on daily glycemic control and lifestyle in patients with type 2 diabetes on premix insulin therapy.
Methods And Results: A total of 172 patients using premix insulin, with HbA1c ≥ 7.0% (56 mmol/mol), or the time below the target (TBR) ≥ 4%, or the coefficient of variation (CV) ≥36% during the screening period, were randomly assigned to retrospective FGM (n = 89) or real-time FGM group (n = 83).
Front Endocrinol (Lausanne)
February 2022
Aim: To explore the chronic effects of metformin on testosterone levels in men with type 2 diabetes mellitus (T2DM).
Methods: This is a secondary analysis of a real-world study evaluating the efficacy and safety of premixed insulin treatment in patients with T2DM 3-month intermittent flash glucose monitoring. Male patients aged 18-60 who were using metformin during the 3-month study period were included as the metformin group.
Ultrathin, transparent, and free-standing films assembled from low-dimensional nanomaterials (LDMs) are promising for various applications, including transparent heaters and membranes. However, the intact separation of the assembled films, especially those with controlled ultrathin thickness from deposited substrates, is a tremendous challenge, particularly for fast peeling off via self-detaching. Herein, we propose a versatile method to rapidly peel off ultrathin assembled LDM films, including three types of carbon nanotubes, vermiculite, Ag nanowires, and carbon nanotube@graphene, by dissolving the MXene interlayer from the layer-by-layer filtered MXene/LDM Janus films using diluted H O .
View Article and Find Full Text PDFIntroduction: Hypoglycemic drugs affect the bone quality and the risk of fractures in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and insulin on bone mineral density (BMD) in T2DM.
Methods: In this single-blinded study, a total of 65 patients with T2DM were randomly assigned into four groups for 52 weeks: the exenatide group ( = 19), dulaglutide group ( = 19), insulin glargine group ( = 10), and placebo ( = 17).
Introduction: Prevalence of sarcopenia has increased in patients with type 2 diabetes. The influence of glucose-lowering drugs on muscles in these patients remains unclear. We aimed to investigate the association between muscle mass/function and glucose-lowering drugs.
View Article and Find Full Text PDFBackground: This study is aimed at investigating whether dapagliflozin adjunct to insulin therapy further improves glycemic control compared to insulin therapy alone in patients with newly diagnosed type 2 diabetes (T2D).
Methods: This single-centre, randomized, controlled, open-labeled trial recruited newly diagnosed T2D patients. Subjects were randomized 1 : 1 to the dapagliflozin add-on to continuous subcutaneous insulin infusion (CSII) group (DAPA) or the CSII therapy group for 5 weeks.